Idiopathic pulmonary fibrosis

Disease description

A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change. Year introduced: 2009

Source: MeSH

References 3

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Journal Year Authors
Nitrite in exhaled breath condensate as a marker of nitrossative stress in the airways of patients with asthma, COPD, and idiopathic pulmonary fibrosis. J Clin Lab Anal. 2010 V. Rihák, P. Zatloukal, J. Chládková, A. Zimulová, Z. Havlínová, J. Chládek
J Clin Lab Anal. 2010;24(5):317-22. doi: 10.1002/jcla.20408. PubMed:20872566
Metallic elements in exhaled breath condensate of patients with interstitial lung diseases. J Breath Res 2009 M. Corradi, O. Acampa, M. Goldoni, E. Adami, P. Apostoli, G. de Palma, A. Pesci, A. Mutti
J Breath Res 2009 Dec;3(4):046003. PubMed:21386196
Docosatetraenoyl LPA is elevated in exhaled breath condensate in idiopathic pulmonary fibrosis. BMC Pulm Med 2014 SB. Montesi, SK. Mathai, LN. Brenner, IA. Gorshkova, EV. Berdyshev, AM. Tager, BS. Shea
BMC Pulm Med 2014 Jan;14:5. PubMed:24468008

Compounds 10

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Nickel PubChem CID: 935
Nitrite PubChem CID: 946
Iron PubChem CID: 23925
Molybdenum PubChem CID: 23932
Chromium PubChem CID: 23976
Copper PubChem CID: 23978
Cobalt PubChem CID: 104730
Silicon PubChem CID: 5461123
Selenium PubChem CID: 6326970
Lysophosphatidic acid PubChem CID: 57369610

MeSH information

MeSH ID D054990
MeSH name Idiopathic Pulmonary Fibrosis