Nickel
Description
Description of Nickel with associated disease summary
Nickel (Ni) is one of the metal indicators of interstitial lung
diseases (ILD) including idiopathic interstitial pneumonia (IIPs) and
sarcoidosis. Higher levels of copper were detected in interstitial lung
diseases patients. The higher levels of nickel and other metallic elements (Cr and Si) in ILD patients may be due to their difficulties of metal removal. Structural
modification in the pulmonary interstitium reduce gaseous exchange and make
lung retain some metals such as Ni, Cr and Si for many years. (J Breath Res. (2009))
Description of disease(s) related to Nickel:
Idiopathic pulmonary fibrosis
One study using inductive coupled plasma mass spectrometry (ICP-MS) to detect nickel and shows that the EBC nickel level in idiopathic pulmonary fibrosis patients are significantly higher than the healthy controls (p < 0.05 versus controls) (J Breath Res. (2009)).Non-specific interstitial pneumonia
One study using inductive coupled plasma mass spectrometry (ICP-MS) to detect nickel and shows that the EBC nickel level in non-specific interstitial pneumonia patients are higher than the healthy controls (p < 0.05 versus controls) (J Breath Res. (2009)).Sarcoidosis
One study using inductive coupled plasma mass spectrometry (ICP-MS) to detect copper and shows that the EBC nickel level in sarcoidosis patients are higher than the healthy controls (p < 0.05 versus controls) (J Breath Res. (2009)).Summary of extracted biomedical information
No extracted biomedical infomation is detected in current reference collection for lack of full text of associated references or no biomedical terms are detected with Nickel in the same sentence by our text-mining approach.
Associated references with human 21
Download references|
Reference title
with link to reference page |
Journal | Year | Authors & PubMed Link |
|---|---|---|---|
| Rare occupational cause of nasal septum perforation: Nickel exposure. | Int J Occup Med Environ Health | 2017 |
EC. Bolek, A. Erden, C. Kulekci, U. Kalyoncu, O. Karadag
Int J Occup Med Environ Health 2017 Oct;30(6):963-967. PubMed:28839290 |
| Reduced graphene oxide-nickel nanoparticles/biopolymer composite films for the sub-millimolar detection of glucose. | Analyst | 2016 |
R. Krishna, JM. Campiña, PM. Fernandes, J. Ventura, E. Titus, AF. Silva
Analyst 2016 Jun;141(13):4151-61. PubMed:27214596 |
| Manganese in exhaled breath condensate: a new marker of exposure to welding fumes. | Toxicol. Lett. | 2014 |
S. Hulo, N. Chérot-Kornobis, M. Howsam, S. Crucq, V. de Broucker, A. Sobaszek, JL. Edme
Toxicol. Lett. 2014 Apr;226(1):63-9. PubMed:24508310 |
| [Urban individual exposure to cadmium and baroreceptor response to posture]. | Clin Ter | 2014 |
A. Sancini, F. Sinibaldi, B. Loreti, S. De Sio, T. Casale, C. Sacco, B. Scala, C. Monti, A. Chighine, S. Bonomi, P. Cirelli, R. Massimi, R. Giubilati, F. Tomei, MV. Rosati
Clin Ter 2014 ;165(3):e205-12. PubMed:24999575 |
| Case report of occupational asthma induced by polyvinyl chloride and nickel. | J. Korean Med. Sci. | 2013 |
GW. Song, GY. Ban, YH. Nam, HS. Park, YM. Ye
J. Korean Med. Sci. 2013 Oct;28(10):1540-2. PubMed:24133363 |
| Health status within the precincts of a nickel-copper mining and smelting environment. | Afr Health Sci | 2011 |
GI. Ekosse
Afr Health Sci 2011 Mar;11(1):90-6. PubMed:21572863 |
| Reconstruction of tracheal wall defect with a mesh patch of nickel-titanium shape-memory alloy. | Ann. Otol. Rhinol. Laryngol. | 2011 |
JS. Luo, PC. Cui, PF. Gao, H. Nan, Z. Liu, YZ. Sun
Ann. Otol. Rhinol. Laryngol. 2011 Mar;120(3):198-203. PubMed:21510146 |
| Urinary elimination of nickel and cobalt in relation to airborne nickel and cobalt exposures in a battery plant. | Int Arch Occup Environ Health | 2007 |
K. Yokota, Y. Johyama, Y. Kunitani, H. Michitsuji, S. Yamada
Int Arch Occup Environ Health 2007 May;80(6):527-31. PubMed:17136408 |
| [Forty-three tracheal stricture with Ni-Ti shape memory alloy stent]. | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | 2005 |
HJ. Yi, BQ. Zhang, W. Liu, PH. Peng, XZ. Shi, Y. Zhang, L. He, H. Jiang, BJ. Wei, F. Qi, ZD. Jiang, XL. Zhu
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2005 Apr;40(4):261-5. PubMed:16008258 |
| Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells. | Physiol. Genomics | 2005 |
A. Vengellur, JM. Phillips, JB. Hogenesch, JJ. LaPres
Physiol. Genomics 2005 Aug;22(3):308-18. PubMed:15942021 |
| Evaluation of the human nickel retention model with workplace data. | Regul. Toxicol. Pharmacol. | 2001 |
CP. Yu, TH. Hsieh, AR. Oller, G. Oberdörster
Regul. Toxicol. Pharmacol. 2001 Apr;33(2):165-72. PubMed:11350199 |
| Cloning of differentially expressed sequence tags from nickel-transformed human embryonic lung cells. | Cancer Lett. | 2000 |
X. Mao, T. Kashii, R. Hayashi, K. Sassa, T. Fujishita, M. Maruyama, M. Kobayashi, S. Liu
Cancer Lett. 2000 Dec;161(1):57-62. PubMed:11078913 |
| Assessment of historical exposures in a nickel refinery in Norway. | Scand J Work Environ Health | 2000 |
TK. Grimsrud, SR. Berge, F. Resmann, T. Norseth, A. Andersen
Scand J Work Environ Health 2000 Aug;26(4):338-45. PubMed:10994800 |
| Occupational exposure to chromium and nickel in the 1980s in Finland. | Sci. Total Environ. | 1997 |
M. Kiilunen
Sci. Total Environ. 1997 Jun;199(1-2):91-101. PubMed:9200851 |
| Persistent neurotoxicity from a battery fire: is cadmium the culprit? | South. Med. J. | 1996 |
KH. Kilburn, KL. McKinley
South. Med. J. 1996 Jul;89(7):693-8. PubMed:8685756 |
| Relation between various chromium compounds and some other elements in fumes from manual metal arc stainless steel welding. | Br J Ind Med | 1993 |
W. Matczak, J. Chmielnicka
Br J Ind Med 1993 Mar;50(3):244-51. PubMed:8457491 |
| Acute nickel carbonyl poisoning. | Am J Emerg Med | 1993 |
DL. Kurta, BS. Dean, EP. Krenzelok
Am J Emerg Med 1993 Jan;11(1):64-6. PubMed:8383493 |
| Cross-shift and chronic effects of stainless-steel welding related to internal dosimetry of chromium and nickel. | Am. J. Ind. Med. | 1990 |
KH. Kilburn, R. Warshaw, CT. Boylen, JC. Thornton, SM. Hopfer, FW. Sunderman, J. Finklea
Am. J. Ind. Med. 1990 ;17(5):607-15. PubMed:2337084 |
| Acute nickel toxicity in electroplating workers who accidently ingested a solution of nickel sulfate and nickel chloride. | Am. J. Ind. Med. | 1988 |
FW. Sunderman, B. Dingle, SM. Hopfer, T. Swift
Am. J. Ind. Med. 1988 ;14(3):257-66. PubMed:3189343 |
| Dust in dental laboratories. Part I: Types and levels in specific operations. | J Prosthet Dent | 1980 |
D. Brune, H. Beltesbrekke
J Prosthet Dent 1980 Jun;43(6):687-92. PubMed:6929337 |
| Lactose intolerance in systemic nickel allergy syndrome. | Int J Immunopathol Pharmacol |
IA. Cazzato, E. Vadrucci, G. Cammarota, M. Minelli, A. Gasbarrini
Int J Immunopathol Pharmacol 2011 Apr-Jun;24(2):535-7. PubMed:21658331 |
Associated curated diseases 3
Download diseasesAssociated disease mapping
Mapping of all associated diseases to Nickel is displayed in red.
|
Disease Name
with link to disease page |
Description of MeSH term
with link to MeSH Database |
Number of references |
|---|---|---|
| Sarcoidosis |
MeSH:
Sarcoidosis
An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually
invades the lungs with fibrosis and may also involve lymph nodes, skin, liver,
spleen, eyes, phalangeal bones, and parotid glands.
Year introduced: PSEUDOTUBERCULOSIS use SARCOIDOSIS 1963-1992
Link to MeSH Database: D012507
|
4 |
| Non Specific Interstitial Pneumonia |
MeSH:
Lung Diseases, Interstitial
A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the
interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung
diseases are classified by their etiology (known or unknown causes), and
radiological-pathological features.
Year introduced: 1994
Link to MeSH Database: D017563
|
1 |
| Idiopathic Pulmonary Fibrosis |
MeSH:
Idiopathic Pulmonary Fibrosis
A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of
breathlessness with exertion and a nonproductive cough, leading to progressive
DYSPNEA. Pathological features show scant interstitial inflammation, patchy
collagen fibrosis, prominent fibroblast proliferation foci, and microscopic
honeycomb change.
Year introduced: 2009
Link to MeSH Database: D054990
|
3 |
Associated abnormalities 0
No associated abnormalities are detected in current reference collection.
There are 21 associated references with Nickel. Due to lack of full text of references or no associated abnormalities are detected in our text-mining workflow, we cannot extract any abnormality terms from the associated reference collection.
Associated chemicals 0
No associated chemicals are detected in current reference collection.
There are 21 associated references with Nickel. Due to lack of full text of references or no associated chemicals are detected in our text-mining workflow, we cannot extract any chemical terms from the associated reference collection.
Associated functions 0
No associated functions are detected in current reference collection.
There are 21 associated references with Nickel. Due to lack of full text of references or no associated functions are detected in our text-mining workflow, we cannot extract any function terms from the associated reference collection.
Associated genes 0
No associated genes are detected in current reference collection.
There are 21 associated references with Nickel. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.
NCBI Entrez Crosslinks
Chemical Information
| Formula | Ni |
| Mass | 58.693 |
| Synonyms | NICKEL 7440-02-0 Raney alloy Fibrex Nickel catalyst Fibrex P Nickel, elemental Nichel [Italian] (63ni)nickel Nickel 207 Nickel, soluble salts niccolum niquel Alcan 756 Metallic nickel Nickel, ion (Ni1+) Nickel compounds NI 0901-S (harshaw) (59ni)nickel CCRIS 427 |
| PubChem CID | 935 |