Description of Nickel with associated disease summary
Idiopathic pulmonary fibrosisOne study using inductive coupled plasma mass spectrometry (ICP-MS) to detect nickel and shows that the EBC nickel level in idiopathic pulmonary fibrosis patients are significantly higher than the healthy controls (p < 0.05 versus controls) (J Breath Res. (2009)).
Non-specific interstitial pneumoniaOne study using inductive coupled plasma mass spectrometry (ICP-MS) to detect nickel and shows that the EBC nickel level in non-specific interstitial pneumonia patients are higher than the healthy controls (p < 0.05 versus controls) (J Breath Res. (2009)).
SarcoidosisOne study using inductive coupled plasma mass spectrometry (ICP-MS) to detect copper and shows that the EBC nickel level in sarcoidosis patients are higher than the healthy controls (p < 0.05 versus controls) (J Breath Res. (2009)).
Summary of extracted biomedical informationNo extracted biomedical infomation is detected in current reference collection for lack of full text of associated references or no biomedical terms are detected with Nickel in the same sentence by our text-mining approach.
Associated references with human 21Download references
with link to reference page
|Journal||Year||Authors & PubMed Link|
|Rare occupational cause of nasal septum perforation: Nickel exposure.||Int J Occup Med Environ Health||2017||
EC. Bolek, A. Erden, C. Kulekci, U. Kalyoncu, O. Karadag
Int J Occup Med Environ Health 2017 Oct;30(6):963-967. PubMed:28839290
|Reduced graphene oxide-nickel nanoparticles/biopolymer composite films for the sub-millimolar detection of glucose.||Analyst||2016||
R. Krishna, JM. Campiña, PM. Fernandes, J. Ventura, E. Titus, AF. Silva
Analyst 2016 Jun;141(13):4151-61. PubMed:27214596
|Manganese in exhaled breath condensate: a new marker of exposure to welding fumes.||Toxicol. Lett.||2014||
S. Hulo, N. Chérot-Kornobis, M. Howsam, S. Crucq, V. de Broucker, A. Sobaszek, JL. Edme
Toxicol. Lett. 2014 Apr;226(1):63-9. PubMed:24508310
|[Urban individual exposure to cadmium and baroreceptor response to posture].||Clin Ter||2014||
A. Sancini, F. Sinibaldi, B. Loreti, S. De Sio, T. Casale, C. Sacco, B. Scala, C. Monti, A. Chighine, S. Bonomi, P. Cirelli, R. Massimi, R. Giubilati, F. Tomei, MV. Rosati
Clin Ter 2014 ;165(3):e205-12. PubMed:24999575
|Case report of occupational asthma induced by polyvinyl chloride and nickel.||J. Korean Med. Sci.||2013||
GW. Song, GY. Ban, YH. Nam, HS. Park, YM. Ye
J. Korean Med. Sci. 2013 Oct;28(10):1540-2. PubMed:24133363
|Health status within the precincts of a nickel-copper mining and smelting environment.||Afr Health Sci||2011||
Afr Health Sci 2011 Mar;11(1):90-6. PubMed:21572863
|Reconstruction of tracheal wall defect with a mesh patch of nickel-titanium shape-memory alloy.||Ann. Otol. Rhinol. Laryngol.||2011||
JS. Luo, PC. Cui, PF. Gao, H. Nan, Z. Liu, YZ. Sun
Ann. Otol. Rhinol. Laryngol. 2011 Mar;120(3):198-203. PubMed:21510146
|Urinary elimination of nickel and cobalt in relation to airborne nickel and cobalt exposures in a battery plant.||Int Arch Occup Environ Health||2007||
K. Yokota, Y. Johyama, Y. Kunitani, H. Michitsuji, S. Yamada
Int Arch Occup Environ Health 2007 May;80(6):527-31. PubMed:17136408
|[Forty-three tracheal stricture with Ni-Ti shape memory alloy stent].||Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi||2005||
HJ. Yi, BQ. Zhang, W. Liu, PH. Peng, XZ. Shi, Y. Zhang, L. He, H. Jiang, BJ. Wei, F. Qi, ZD. Jiang, XL. Zhu
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2005 Apr;40(4):261-5. PubMed:16008258
|Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells.||Physiol. Genomics||2005||
A. Vengellur, JM. Phillips, JB. Hogenesch, JJ. LaPres
Physiol. Genomics 2005 Aug;22(3):308-18. PubMed:15942021
|Evaluation of the human nickel retention model with workplace data.||Regul. Toxicol. Pharmacol.||2001||
CP. Yu, TH. Hsieh, AR. Oller, G. Oberdörster
Regul. Toxicol. Pharmacol. 2001 Apr;33(2):165-72. PubMed:11350199
|Cloning of differentially expressed sequence tags from nickel-transformed human embryonic lung cells.||Cancer Lett.||2000||
X. Mao, T. Kashii, R. Hayashi, K. Sassa, T. Fujishita, M. Maruyama, M. Kobayashi, S. Liu
Cancer Lett. 2000 Dec;161(1):57-62. PubMed:11078913
|Assessment of historical exposures in a nickel refinery in Norway.||Scand J Work Environ Health||2000||
TK. Grimsrud, SR. Berge, F. Resmann, T. Norseth, A. Andersen
Scand J Work Environ Health 2000 Aug;26(4):338-45. PubMed:10994800
|Occupational exposure to chromium and nickel in the 1980s in Finland.||Sci. Total Environ.||1997||
Sci. Total Environ. 1997 Jun;199(1-2):91-101. PubMed:9200851
|Persistent neurotoxicity from a battery fire: is cadmium the culprit?||South. Med. J.||1996||
KH. Kilburn, KL. McKinley
South. Med. J. 1996 Jul;89(7):693-8. PubMed:8685756
|Relation between various chromium compounds and some other elements in fumes from manual metal arc stainless steel welding.||Br J Ind Med||1993||
W. Matczak, J. Chmielnicka
Br J Ind Med 1993 Mar;50(3):244-51. PubMed:8457491
|Acute nickel carbonyl poisoning.||Am J Emerg Med||1993||
DL. Kurta, BS. Dean, EP. Krenzelok
Am J Emerg Med 1993 Jan;11(1):64-6. PubMed:8383493
|Cross-shift and chronic effects of stainless-steel welding related to internal dosimetry of chromium and nickel.||Am. J. Ind. Med.||1990||
KH. Kilburn, R. Warshaw, CT. Boylen, JC. Thornton, SM. Hopfer, FW. Sunderman, J. Finklea
Am. J. Ind. Med. 1990 ;17(5):607-15. PubMed:2337084
|Acute nickel toxicity in electroplating workers who accidently ingested a solution of nickel sulfate and nickel chloride.||Am. J. Ind. Med.||1988||
FW. Sunderman, B. Dingle, SM. Hopfer, T. Swift
Am. J. Ind. Med. 1988 ;14(3):257-66. PubMed:3189343
|Dust in dental laboratories. Part I: Types and levels in specific operations.||J Prosthet Dent||1980||
D. Brune, H. Beltesbrekke
J Prosthet Dent 1980 Jun;43(6):687-92. PubMed:6929337
|Lactose intolerance in systemic nickel allergy syndrome.||Int J Immunopathol Pharmacol||
IA. Cazzato, E. Vadrucci, G. Cammarota, M. Minelli, A. Gasbarrini
Int J Immunopathol Pharmacol 2011 Apr-Jun;24(2):535-7. PubMed:21658331
Associated curated diseases 3Download diseases
Associated disease mapping
Mapping of all associated diseases to Nickel is displayed in red.
with link to disease page
Description of MeSH term
with link to MeSH Database
|Number of references|
An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands. Year introduced: PSEUDOTUBERCULOSIS use SARCOIDOSIS 1963-1992Link to MeSH Database: D012507
|Non Specific Interstitial Pneumonia||
Lung Diseases, Interstitial
A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features. Year introduced: 1994Link to MeSH Database: D017563
|Idiopathic Pulmonary Fibrosis||
Idiopathic Pulmonary Fibrosis
A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change. Year introduced: 2009Link to MeSH Database: D054990
Associated abnormalities 0
No associated abnormalities are detected in current reference collection.
There are 21 associated references with Nickel. Due to lack of full text of references or no associated abnormalities are detected in our text-mining workflow, we cannot extract any abnormality terms from the associated reference collection.
Associated chemicals 0
No associated chemicals are detected in current reference collection.
There are 21 associated references with Nickel. Due to lack of full text of references or no associated chemicals are detected in our text-mining workflow, we cannot extract any chemical terms from the associated reference collection.
Associated functions 0
No associated functions are detected in current reference collection.
There are 21 associated references with Nickel. Due to lack of full text of references or no associated functions are detected in our text-mining workflow, we cannot extract any function terms from the associated reference collection.
Associated genes 0
No associated genes are detected in current reference collection.
There are 21 associated references with Nickel. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.
NCBI Entrez Crosslinks
Nickel, soluble salts
Nickel, ion (Ni1+)
NI 0901-S (harshaw)