Obstructive sleep apnea
Disease description
A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395) Year introduced: 2000
Source: MeSHReferences 7
Download references
Title
with link to reference page |
Journal | Year | Authors |
---|---|---|---|
Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients. | Chest | 2002 |
GE. Carpagnano, SA. Kharitonov, O. Resta, MP. Foschino-Barbaro, E. Gramiccioni, PJ. Barnes
Chest 2002 Oct;122(4):1162-7. PubMed:12377837 |
Exhaled pH, exhaled nitric oxide, and induced sputum cellularity in obese patients with obstructive sleep apnea syndrome. | Transl Res | 2008 |
GE. Carpagnano, A. Spanevello, R. Sabato, A. Depalo, V. Turchiarelli, MP. Foschino Barbaro
Transl Res 2008 Jan;151(1):45-50. PubMed:18061127 |
Exhaled breath markers in patients with obstructive sleep apnoea. | Sleep Breath | 2008 |
M. Petrosyan, E. Perraki, D. Simoes, I. Koutsourelakis, E. Vagiakis, C. Roussos, C. Gratziou
Sleep Breath 2008 Aug;12(3):207-15. PubMed:18074162 |
Airway inflammation in obstructive sleep apnea: is leptin the missing link? | Respir Med | 2008 |
S. Antonopoulou, S. Loukides, G. Papatheodorou, C. Roussos, M. Alchanatis
Respir Med 2008 Oct;102(10):1399-405. PubMed:18606530 |
Correlation of 8-isoprostane, interleukin-6 and cardiac functions with clinical score in childhood obstructive sleep apnoea. | Acta Paediatr. | 2008 |
MA. Biltagi, MA. Maguid, MA. Ghafar, E. Farid
Acta Paediatr. 2008 Oct;97(10):1397-405. PubMed:18631340 |
Oxidative stress and inflammatory markers in the exhaled breath condensate of children with OSA. | Sleep Breath. | 2012 |
G. Malakasioti, E. Alexopoulos, C. Befani, K. Tanou, V. Varlami, D. Ziogas, P. Liakos, K. Gourgoulianis, AG. Kaditis
Sleep Breath. 2012 Sep;16(3):703-8. doi: 10.1007/s11325-011-0560-7. Epub 2011 Aug 3. PubMed:21811879 |
Urates in exhaled breath condensate of children with obstructive sleep apnea. | Biochem Med (Zagreb). | 2011 |
V. Vlasic, J. Trifunovic, I. Cepelak, P. Nimac, RZ. Topic, S. Dodig
Biochem Med (Zagreb). 2011;21(2):139-44. PubMed:22135853 |
Compounds 4
Download compoundsHydrogen peroxide | PubChem CID: 784 |
Uric acid | PubChem CID: 1175 |
Nitric oxide | PubChem CID: 145068 |
8-epi-PGF2alpha | PubChem CID: 5282263 |
MeSH information
MeSH ID | D020181 |
MeSH name | Sleep Apnea, Obstructive |