Asbestosis

Disease description

A form of pneumoconiosis caused by inhalation of asbestos fibers which elicit potent inflammatory responses in the parenchyma of the lung. The disease is characterized by interstitial fibrosis of the lung, varying from scattered sites to extensive scarring of the alveolar interstitium.

Source: MeSH

References 4

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Journal Year Authors
Increased alveolar nitric oxide concentration and high levels of leukotriene B(4) and 8-isoprostane in exhaled breath condensate in patients with asbestosis. Thorax 2007 H. Lehtonen, P. Oksa, L. Lehtimäki, A. Sepponen, R. Nieminen, H. Kankaanranta, S. Saarelainen, R. Järvenpää, J. Uitti, E. Moilanen
Thorax 2007 Jul;62(7):602-7. PubMed:17251310
Determination of 8-iso-prostaglandin F(2alpha) in exhaled breath condensate using combination of immunoseparation and LC-ESI-MS/MS. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2008 K. Syslová, P. Kacer, M. Kuzma, P. Klusácková, Z. Fenclová, J. Lebedová, D. Pelclová
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2008 May;867(1):8-14. PubMed:18373964
Reproducibility of exhaled breath condensate markers. Eur. Respir. J. 2008 S. Chow, DH. Yates, PS. Thomas
Eur. Respir. J. 2008 Oct;32(4):1124-6. PubMed:18827164
LC-ESI-MS/MS method for oxidative stress multimarker screening in the exhaled breath condensate of asbestosis/silicosis patients. J Breath Res 2010 K. Syslová, P. Kačer, M. Kuzma, A. Pankrácová, Z. Fenclová, S. Vlčková, J. Lebedová, D. Pelclová
J Breath Res 2010 Mar;4(1):017104. PubMed:21386209

Compounds 4

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DL-o-Tyrosine PubChem CID: 91482
Nitric oxide PubChem CID: 145068
8-epi-PGF2alpha PubChem CID: 5282263
8-hydroxy-2-deoxy Guanosine PubChem CID: 53394351

MeSH information

MeSH ID D001195
MeSH name Asbestosis