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37 kBq 14C-urea breath test and gastric biopsy analyses of H. pylori infection.
RA. Allardyce, BA. Chapman, AB. Tie, MJ. Burt, KJ. Yeo, JI. Keenan, PF. Bagshaw
Aust N Z J Surg 1997 Jan;67(1):31-4.
PubMed: 9033373
Abstract
The treatment of H. pylori-associated gastroduodenal disease is increasingly aimed at bacterial eradication which requires follow-up assessment of therapeutic effectiveness and re-infection. A simplified 37 kBq 14C-urea breath test for H. pylori infection has been developed. The 37 kBq 14C-urea breath test was compared with biopsy urease (CLO) and histological analyses of gastric-biopsies obtained from 63 patients undergoing endoscopy. The 30-min breath test correlated closely with biopsy findings, had a sensitivity of 100%, a specificity of 95% and a positive predictive value of 92%. The simplified, low-dose, 14C-urea breath test is a convenient, low-cost, transportable means of facilitating the management of H. pylori-associated diseases.
Associated compounds:
Compound Name
with link to compound page |
Structure | Number of references |
---|---|---|
Urea | 1130 |