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Selective diagnosis of diabetes using Pt-functionalized WO3 hemitube networks as a sensing layer of acetone in exhaled breath.
SJ. Choi, I. Lee, BH. Jang, DY. Youn, WH. Ryu, CO. Park, ID. Kim
Anal. Chem. 2013 Feb;85(3):1792-6.
PubMed: 23252728
Abstract
Thin-walled WO(3) hemitubes and catalytic Pt-functionalized WO(3) hemitubes were synthesized via a polymeric fiber-templating route and used as exhaled breath sensing layers for potential diagnosis of halitosis and diabetes through the detection of H(2)S and CH(3)COCH(3), respectively. Pt-functionalized WO(3) hemitubes with wall thickness of 60 nm exhibited superior acetone sensitivity (R(air)/R(gas) = 4.11 at 2 ppm) with negligible H(2)S response, and pristine WO(3) hemitubes showed a 4.90-fold sensitivity toward H(2)S with minimal acetone-sensing characteristics. The detection limit (R(air)/R(gas)) of the fabricated sensors with Pt-functionalized WO(3) hemitubes was 1.31 for acetone of 120 ppb, and pristine WO(3) hemitubes showed a gas response of 1.23 at 120 ppb of H(2)S. Long-term stability tests revealed that the remarkable selectivity has been maintained after aging for 7 months in air. The superior cross-sensitivity and response to H(2)S and acetone gas offer a potential platform for application in diabetes and halitosis diagnosis.
Associated compounds:
Compound Name
with link to compound page |
Structure | Number of references |
---|---|---|
Acetone | 275 |