Isopropanol
Description
Description of isopropanol with associated disease summary
Chronic obstructive pulmonary disease (COPD)
The concentration of EBC 2-propanol is increased in COPD patients (J Proteome Res. (2013)) . Although 2-propanol can be formed from reduction of acetone by alcohol dehydrogenase in liver, no acetone variation were detected. (J Proteome Res. (2013)). More studies has to be performed to explain the relation between alcohols and smoking-related diseases.Pulmonary Langerhans cell histiocytosis (PLCH)
The concentration of EBC 2-propanol is increased in PLCH patients (J Proteome Res. (2013)) . Although 2-propanol can be formed from reduction of acetone by alcohol dehydrogenase in liver, no acetone variation were detected. (J Proteome Res. (2013)). More studies has to be performed to explain the relation between alcohols and smoking-related diseases.Disease summary
Cystic fibrosis (CF)
The concentration of EBC 2-propanol is increased in CF patients (Thorax. (2012)). The increase of 2-propanol may be due to metabolism in bacteria and/or increased lipid degradation and lipid peroxidation.Summary of extracted biomedical information
The involved biomedical functions are known as Skin Absorption, Biochemical Reaction and Disinfectants. Isopropanol is associated with acetonitrile and Propylene Glycols.Associated references with human 27
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Reference title
with link to reference page |
Journal | Year | Authors & PubMed Link |
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Bio-sniffer (gas-phase biosensor) with secondary alcohol dehydrogenase (S-ADH) for determination of isopropanol in exhaled air as a potential volatile biomarker. | Biosens Bioelectron | 2017 |
PJ. Chien, T. Suzuki, M. Tsujii, M. Ye, K. Toma, T. Arakawa, Y. Iwasaki, K. Mitsubayashi
Biosens Bioelectron 2017 May;91:341-346. PubMed:28043076 |
Breath gas concentrations mirror exposure to sevoflurane and isopropyl alcohol in hospital environments in non-occupational conditions. | J Breath Res | 2016 |
M. Castellanos, G. Xifra, JM. Fernández-Real, JM. Sánchez
J Breath Res 2016 Jan;10(1):016001. PubMed:26824193 |
Alcohol increases bonding between the tracheal tube and the tracheal tube connector. | A A Case Rep | 2015 |
P. Mullick, A. Kumar, S. Prakash
A A Case Rep 2015 May;4(9):114-6. PubMed:25909775 |
A review of the volatiles from the healthy human body. | J Breath Res | 2014 |
B. de Lacy Costello, A. Amann, H. Al-Kateb, C. Flynn, W. Filipiak, T. Khalid, D. Osborne, NM. Ratcliffe
J Breath Res 2014 Mar;8(1):014001. PubMed:24421258 |
Separating smoking-related diseases using NMR-based metabolomics of exhaled breath condensate. | J. Proteome Res. | 2013 |
G. de Laurentiis, D. Paris, D. Melck, P. Montuschi, M. Maniscalco, A. Bianco, M. Sofia, A. Motta
J. Proteome Res. 2013 Mar;12(3):1502-11. PubMed:23360153 |
NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis. | Thorax. | 2012 |
P. Montuschi, D. Paris, D. Melck, V. Lucidi, G. Ciabattoni, V. Raia, C. Calabrese, A. Bush, PJ. Barnes, A. Motta
Thorax. 2012 Mar;67(3):222-8. doi: 10.1136/thoraxjnl-2011-200072. Epub 2011 Nov 21. PubMed:22106016 |
Exhaled aerosol transmission of pandemic and seasonal H1N1 influenza viruses in the ferret. | PLoS ONE | 2012 |
F. Koster, K. Gouveia, Y. Zhou, K. Lowery, R. Russell, H. MacInnes, Z. Pollock, RC. Layton, J. Cromwell, D. Toleno, J. Pyle, M. Zubelewicz, K. Harrod, R. Sampath, S. Hofstadler, P. Gao, Y. Liu, YS. Cheng
PLoS ONE 2012 ;7(4):e33118. PubMed:22509254 |
Assessment of exposure to alcohol vapor from alcohol-based hand rubs. | Int J Environ Res Public Health | 2012 |
V. Bessonneau, O. Thomas
Int J Environ Res Public Health 2012 03;9(3):868-79. PubMed:22690169 |
Demonstration that methadone is being present in the exhaled breath aerosol fraction. | J Pharm Biomed Anal | 2011 |
O. Beck, S. Sandqvist, J. Franck
J Pharm Biomed Anal 2011 Dec;56(5):1024-8. PubMed:21873017 |
Eurasian-origin gene segments contribute to the transmissibility, aerosol release, and morphology of the 2009 pandemic H1N1 influenza virus. | PLoS Pathog. | 2011 |
SS. Lakdawala, EW. Lamirande, AL. Suguitan, W. Wang, CP. Santos, L. Vogel, Y. Matsuoka, WG. Lindsley, H. Jin, K. Subbarao
PLoS Pathog. 2011 Dec;7(12):e1002443. PubMed:22241979 |
Biomarkers of recent drinking, retrograde extrapolation of blood-alcohol concentration and plasma-to-blood distribution ratio in a case of driving under the influence of alcohol. | J Forensic Leg Med | 2011 |
AW. Jones
J Forensic Leg Med 2011 Jul;18(5):213-6. PubMed:21663869 |
Quantitative assessment of airborne exposures generated during common cleaning tasks: a pilot study. | Environ Health | 2010 |
A. Bello, MM. Quinn, MJ. Perry, DK. Milton
Environ Health 2010 Nov;9:76. PubMed:21118559 |
Subclinical responses in healthy cyclists briefly exposed to traffic-related air pollution: an intervention study. | Environ Health | 2010 |
L. Jacobs, TS. Nawrot, B. de Geus, R. Meeusen, B. Degraeuwe, A. Bernard, M. Sughis, B. Nemery, LI. Panis
Environ Health 2010 Oct;9:64. PubMed:20973949 |
Characterization of occupational exposures to cleaning products used for common cleaning tasks--a pilot study of hospital cleaners. | Environ Health | 2009 |
A. Bello, MM. Quinn, MJ. Perry, DK. Milton
Environ Health 2009 Mar;8:11. PubMed:19327131 |
Ethanol-based cleanser versus isopropyl alcohol to decontaminate stethoscopes. | Am J Infect Control | 2009 |
P. Lecat, E. Cropp, G. McCord, NA. Haller
Am J Infect Control 2009 Apr;37(3):241-3. PubMed:19185394 |
Dissolved VOC concentrations and salt contents affecting air-sweat equilibrium partition of hydrophilic and hydrophobic VOCs. | J Environ Sci Health A Tox Hazard Subst Environ Eng | 2008 |
WH. Cheng
J Environ Sci Health A Tox Hazard Subst Environ Eng 2008 Jan;43(1):98-104. PubMed:18161563 |
An adaptive breath sampler for use with human subjects with an impaired respiratory function. | Analyst | 2007 |
M. Basanta, T. Koimtzis, D. Singh, I. Wilson, CL. Thomas
Analyst 2007 Feb;132(2):153-63. PubMed:17260076 |
Can alcohol-based hand-rub solutions cause you to lose your driver's license? Comparative cutaneous absorption of various alcohols. | Antimicrob. Agents Chemother. | 2007 |
TL. Brown, S. Gamon, P. Tester, R. Martin, K. Hosking, GC. Bowkett, D. Gerostamoulos, ML. Grayson
Antimicrob. Agents Chemother. 2007 Mar;51(3):1107-8. PubMed:17194820 |
The analysis of 1-propanol and 2-propanol in humid air samples using selected ion flow tube mass spectrometry. | Rapid Commun. Mass Spectrom. | 2006 |
T. Wang, W. Carroll, W. Lenny, P. Boit, D. Smith
Rapid Commun. Mass Spectrom. 2006 ;20(2):125-30. PubMed:16331744 |
Gas chromatography-mass spectroscopy analysis of emissions from cement when using ultrasonically driven tools. | Acta Orthop | 2005 |
SB. Shewale, RD. Briggs
Acta Orthop 2005 Oct;76(5):647-50. PubMed:16263610 |
Personal exposure to ultrafine particles and oxidative DNA damage. | Environ. Health Perspect. | 2005 |
PS. Vinzents, P. Møller, M. Sørensen, LE. Knudsen, O. Hertel, FP. Jensen, B. Schibye, S. Loft
Environ. Health Perspect. 2005 Nov;113(11):1485-90. PubMed:16263500 |
Grand rounds: latex-induced occupational asthma in a surgical pathologist. | Environ. Health Perspect. | 2005 |
J. Green-McKenzie, D. Hudes
Environ. Health Perspect. 2005 Jul;113(7):888-93. PubMed:16002378 |
Urinary sevoflurane and hexafluoro-isopropanol as biomarkers of low-level occupational exposure to sevoflurane. | Int Arch Occup Environ Health | 2005 |
A. Accorsi, B. Morrone, I. Domenichini, S. Valenti, GB. Raffi, FS. Violante
Int Arch Occup Environ Health 2005 Jun;78(5):369-78. PubMed:15864632 |
Breathing and heart rate during experimental solvent exposure of young adults with self-reported multiple chemical sensitivity (sMCS). | Neurotoxicology | 2003 |
K. Haumann, E. Kiesswetter, C. van Thriel, M. Blaszkewicz, K. Golka, A. Seeber
Neurotoxicology 2003 Mar;24(2):179-86. PubMed:12606290 |
Comparison of models for the estimation of biological partition coefficients. | J. Toxicol. Environ. Health Part A | 2002 |
MP. Payne, LC. Kenny
J. Toxicol. Environ. Health Part A 2002 Jul;65(13):897-931. PubMed:12133236 |
Acute sensory irritation from exposure to isopropanol (2-propanol) at TLV in workers and controls: objective versus subjective effects. | Ann Occup Hyg | 2002 |
MA. Smeets, C. Mauté, PH. Dalton
Ann Occup Hyg 2002 Jun;46(4):359-73. PubMed:12176705 |
Analysis of 2-propanol in exhaled breath using in situ enrichment and cataluminescence detection. | Luminescence |
Y. Wu, F. Wen, D. Liu, H. Kong, C. Zhang, S. Zhang
Luminescence 2011 Mar-Apr;26(2):125-9. PubMed:20155729 |
Associated curated diseases 3
Download diseasesAssociated disease mapping
Mapping of all associated diseases to isopropanol is displayed in red.
Disease Name
with link to disease page |
Description of MeSH term
with link to MeSH Database |
Number of references |
---|---|---|
Cystic Fibrosis |
MeSH:
Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE
REGULATOR expressed in several organs including the LUNG, the PANCREAS, the
BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by
epithelial secretory dysfunction associated with ductal obstruction resulting in
AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY;
maldigestion; salt depletion; and HEAT PROSTRATION.
Year introduced: 1967
Link to MeSH Database: D003550
|
20 |
Pulmonary Langerhans Cell Histiocytosis |
MeSH:
Histiocytosis, Langerhans-Cell
A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic
Birbeck granules (X bodies), or by monoclonal antibody staining for their surface
CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can
be a systemic disorder.
Year introduced: 1990(1975)
Link to MeSH Database: D006646
|
1 |
Chronic Obstructive Pulmonary Disease (Copd) |
MeSH:
Pulmonary Disease, Chronic Obstructive
A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
Year introduced: 2002
Link to MeSH Database: D029424
|
31 |
Associated abnormalities 0
No associated abnormalities are detected in current reference collection.
There are 27 associated references with isopropanol. Due to lack of full text of references or no associated abnormalities are detected in our text-mining workflow, we cannot extract any abnormality terms from the associated reference collection.
Associated chemicals 0
No associated chemicals are detected in current reference collection.
There are 27 associated references with isopropanol. Due to lack of full text of references or no associated chemicals are detected in our text-mining workflow, we cannot extract any chemical terms from the associated reference collection.
Associated functions 0
No associated functions are detected in current reference collection.
There are 27 associated references with isopropanol. Due to lack of full text of references or no associated functions are detected in our text-mining workflow, we cannot extract any function terms from the associated reference collection.
Associated genes 0
No associated genes are detected in current reference collection.
There are 27 associated references with isopropanol. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.
NCBI Entrez Crosslinks
Chemical Information
Formula | C3H8O |
Mass | 60.096 |
Synonyms | isopropanol 2-Propanol Isopropyl alcohol Propan-2-ol 67-63-0 2-Hydroxypropane Alcojel Alkolave Avantine Hartosol Dimethylcarbinol sec-Propyl alcohol Petrohol Takineocol Avantin i-Propanol 1-Methylethanol 2-Propyl alcohol Alcolo Isohol |
PubChem CID | 3776 |