Nitrate

Summary of extracted biomedical information

nitrate is associated with abnormalities such as Acute mountain sickness, Heart failure, Hypertension, Pulmonary and Brachial artery occlusion. The involved biomedical functions are known as Ingestion, nitrate assimilation, Hypoxia, Regulation and Exhalation. The associated genes/proteins with nitrate are Operon, effector domain, mutant gene, Genes, Essential and NIT2 gene. nitrate is associated with Nitrate, Ammonium, NITRATE AND NITRITE, Nitrogen and Nitrite.
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Journal Year Authors & PubMed Link
The Effect of a Dietary Nitrate Supplementation in the Form of a Single Shot of Beetroot Juice on Static and Dynamic Apnea Performance. Int J Sport Nutr Exerc Metab 2018 MJ. Barlow, A. Elia, OM. Shannon, A. Zacharogianni, A. Lodin-Sundstrom
Int J Sport Nutr Exerc Metab 2018 Sep;28(5):497-501. PubMed:29091471
The effect of dietary nitrate supplementation on the spatial heterogeneity of quadriceps deoxygenation during heavy-intensity cycling. Physiol Rep 2017 BC. Breese, DC. Poole, D. Okushima, SJ. Bailey, AM. Jones, N. Kondo, T. Amano, S. Koga
Physiol Rep 2017 Jul;5(14):. PubMed:28743821
Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m). Nitric Oxide 2017 HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill
Nitric Oxide 2017 Sep;69:1-9. PubMed:28684191
Effect of Dietary Nitrate Supplementation on Swimming Performance in Trained Swimmers. Int J Sport Nutr Exerc Metab 2017 S. Lowings, OM. Shannon, K. Deighton, J. Matu, MJ. Barlow
Int J Sport Nutr Exerc Metab 2017 Aug;27(4):377-384. PubMed:28182502
Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp. Nitric Oxide 2016 PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin
Nitric Oxide 2016 11;60:24-31. PubMed:27593617
Changes in breathomics from a 1-year randomized smoking cessation trial of electronic cigarettes. Eur. J. Clin. Invest. 2016 D. Campagna, F. Cibella, P. Caponnetto, MD. Amaradio, M. Caruso, JB. Morjaria, M. Malerba, R. Polosa
Eur. J. Clin. Invest. 2016 Aug;46(8):698-706. PubMed:27322745
Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case. Clin Med Res 2016 CP. Kerley, E. Kilbride, P. Greally, B. Elnazir
Clin Med Res 2016 Dec;14(3-4):151-155. PubMed:27630187
Acute Dietary Nitrate Intake Improves Muscle Contractile Function in Patients With Heart Failure: A Double-Blind, Placebo-Controlled, Randomized Trial. Circ Heart Fail 2015 AR. Coggan, JL. Leibowitz, CA. Spearie, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, K. Mahmood, S. Park, S. Waller, M. Farmer, LR. Peterson
Circ Heart Fail 2015 Sep;8(5):914-20. PubMed:26179185
5-Fluorouracil cardiotoxicity: reversible left ventricular systolic dysfunction with early detection. BMJ Case Rep 2015 MZ. Iskandar, W. Quasem, M. El-Omar
BMJ Case Rep 2015 May;2015:. PubMed:25935919
Acute Beetroot Juice Supplementation Does Not Improve Cycling Performance in Normoxia or Moderate Hypoxia. Int J Sport Nutr Exerc Metab 2015 KE. MacLeod, SF. Nugent, SI. Barr, MS. Koehle, BC. Sporer, MJ. MacInnis
Int J Sport Nutr Exerc Metab 2015 Aug;25(4):359-66. PubMed:25811674
Effects of hyperbaric oxygen on nitric oxide generation in humans. Nitric Oxide 2015 J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg
Nitric Oxide 2015 Jan;44:88-97. PubMed:25498903
Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women. Nitric Oxide 2015 AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson
Nitric Oxide 2015 Aug;48:16-21. PubMed:25199856
Longitudinal decline in pulmonary diffusing capacity among nitrate fertilizer workers. Occup Med (Lond) 2014 KH. Hovland, M. Skogstad, B. Bakke, Ø. Skare, K. Skyberg
Occup Med (Lond) 2014 Apr;64(3):181-7. PubMed:24514575
Smoking attenuates the age-related decrease in IgE levels and maintains eosinophilic inflammation. Clin. Exp. Allergy 2013 T. Nagasaki, H. Matsumoto, H. Nakaji, A. Niimi, I. Ito, T. Oguma, S. Muro, H. Inoue, T. Iwata, T. Tajiri, Y. Kanemitsu, M. Mishima
Clin. Exp. Allergy 2013 Jun;43(6):608-15. PubMed:23711122
Effects of dietary inorganic nitrate on static and dynamic breath-holding in humans. Respir Physiol Neurobiol 2013 TA. Schiffer, FJ. Larsen, JO. Lundberg, E. Weitzberg, P. Lindholm
Respir Physiol Neurobiol 2013 Jan;185(2):339-48. PubMed:23099220
Ventilation, oxidative stress, and nitric oxide in hypobaric versus normobaric hypoxia. Med Sci Sports Exerc 2013 R. Faiss, V. Pialoux, C. Sartori, C. Faes, O. Dériaz, GP. Millet
Med Sci Sports Exerc 2013 Feb;45(2):253-60. PubMed:22895381
Oxidized-LDL and paraoxonase-1 as biomarkers of coronary artery disease in patients with sleep-disordered breathing. Curr. Med. Chem. 2012 FS. Hackenhaar, D. Martinez, TM. Medeiros, C. Klein, PV. Alabarse, MV. Wainstein, SC. Gonçalves, MS. Benfato
Curr. Med. Chem. 2012 ;19(25):4359-66. PubMed:22934769
Exhaled breath condensate nitrates, but not nitrites or FENO, relate to asthma control. Respir Med 2011 A. Malinovschi, S. Pizzimenti, S. Sciascia, E. Heffler, I. Badiu, G. Rolla
Respir Med 2011 Jul;105(7):1007-13. PubMed:21277184
Circulating nitric oxide products do not solely reflect nitric oxide release in cirrhosis and portal hypertension. Liver Int. 2011 P. Afzelius, N. Bazeghi, P. Bie, F. Bendtsen, J. Vestbo, S. Møller
Liver Int. 2011 Oct;31(9):1381-7. PubMed:21745317
Increased plasma and salivary nitrite and decreased bronchial contribution to exhaled NO in pulmonary arterial hypertension. Eur. J. Clin. Invest. 2011 A. Malinovschi, D. Henrohn, A. Eriksson, JO. Lundberg, K. Alving, G. Wikström
Eur. J. Clin. Invest. 2011 Aug;41(8):889-97. PubMed:21554268
No effect of metabolic acidosis on nitric oxide production in hypoxic and hyperoxic lung regions in pigs. Acta Physiol (Oxf) 2011 MC. Nilsson, F. Fredén, P. Wiklund, K. Hambraeus-Jonzon
Acta Physiol (Oxf) 2011 May;202(1):59-68. PubMed:21251235
Impact of chorioamnionitis on exhaled nitric oxide and endotracheal aspirate levels of nitrites-nitrates and interleukin-8 in mechanically ventilated preterm neonates. Pediatr. Pulmonol. 2011 J. Figueras-Aloy, MD. Salvia-Roiges, JM. Rodriguez-Miguélez, X. Miracle-Echegoyen, F. Botet-Mussons, JL. Marín-Soria, X. Carbonell-Estrany
Pediatr. Pulmonol. 2011 Jun;46(6):595-603. PubMed:21246759
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers. Cephalalgia 2010 BJ. Van der Schueren, FH. Verbrugge, R. Verbesselt, A. Van Hecken, M. Depré, JN. de Hoon
Cephalalgia 2010 Nov;30(11):1354-65. PubMed:20959430
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome. J. Pediatr. Hematol. Oncol. 2010 KJ. Sullivan, N. Kissoon, E. Sandler, C. Gauger, M. Froyen, L. Duckworth, M. Brown, S. Murphy
J. Pediatr. Hematol. Oncol. 2010 Oct;32(7):e249-58. PubMed:20724949
Diuretic, opiate and nitrate use in severe acidotic acute cardiogenic pulmonary oedema: analysis from the 3CPO trial. QJM 2010 A. Gray, S. Goodacre, M. Seah, S. Tilley
QJM 2010 Aug;103(8):573-81. PubMed:20511258
Serum nitrite and nitrate levels in children with obstructive sleep-disordered breathing. Sleep Med. 2010 A. Kaditis, E. Alexopoulos, G. Ntamagka, K. Chaidas, A. Karathanasi, S. Gougoura, AA. Papathanasiou, P. Liakos, E. Zintzaras, K. Gourgoulianis
Sleep Med. 2010 Mar;11(3):258-62. PubMed:20153977
Low-dose sodium nitrite vasodilates hypoxic human pulmonary vasculature by a means that is not dependent on a simultaneous elevation in plasma nitrite. Am. J. Physiol. Heart Circ. Physiol. 2010 TE. Ingram, AG. Pinder, DM. Bailey, AG. Fraser, PE. James
Am. J. Physiol. Heart Circ. Physiol. 2010 Feb;298(2):H331-9. PubMed:19940079
Long-term measurements of NO(3) radical at a semiarid urban site: 1. Extreme concentration events and their oxidation capacity. Environ. Sci. Technol. 2009 D. Asaf, D. Pedersen, V. Matveev, M. Peleg, C. Kern, J. Zingler, U. Platt, M. Luria
Environ. Sci. Technol. 2009 Dec;43(24):9117-23. PubMed:20000501
Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma. Ann. Allergy Asthma Immunol. 2009 V. Mehta, JR. Stokes, A. Berro, FA. Romero, TB. Casale
Ann. Allergy Asthma Immunol. 2009 Jul;103(1):31-7. PubMed:19663124
[Inflammation markers in the exhaled air of patients with bronchiectasis unassociated with cystic fibrosis]. Arch. Bronconeumol. 2009 M. Palop-Cervera, A. de Diego Damiá, E. Martínez-Moragón, J. Cortijo, J. Fullana, M. León
Arch. Bronconeumol. 2009 Dec;45(12):597-602. PubMed:19875219
Lack of modulation of gastric emptying by dietary nitrate in healthy volunteers. Tohoku J. Exp. Med. 2009 S. Terai, K. Iijima, K. Asanuma, N. Ara, K. Uno, Y. Abe, T. Koike, A. Imatani, S. Ohara, T. Shimosegawa
Tohoku J. Exp. Med. 2009 May;218(1):73-9. PubMed:19398876
Basal and induced NO formation in the pharyngo-oral tract influences estimates of alveolar NO levels. J. Appl. Physiol. 2009 A. Malinovschi, C. Janson, L. Holm, L. Nordvall, K. Alving
J. Appl. Physiol. 2009 Feb;106(2):513-9. PubMed:19036899
Nitric oxide production in the exhaled air of patients with pulmonary tuberculosis in relation to HIV co-infection. BMC Infect. Dis. 2008 J. Idh, A. Westman, D. Elias, F. Moges, A. Getachew, A. Gelaw, T. Sundqvist, T. Forslund, A. Alemu, B. Ayele, E. Diro, E. Melese, Y. Wondmikun, S. Britton, O. Stendahl, T. Schön
BMC Infect. Dis. 2008 Oct;8:146. PubMed:18950489
Effect of growth hormone therapy on nitric oxide formation in cystic fibrosis patients. Eur. Respir. J. 2008 C. Grasemann, F. Ratjen, D. Schnabel, E. Reutershahn, U. Vester, H. Grasemann
Eur. Respir. J. 2008 Apr;31(4):815-21. PubMed:18094013
Exhaled methyl nitrate as a noninvasive marker of hyperglycemia in type 1 diabetes. Proc. Natl. Acad. Sci. U.S.A. 2007 BJ. Novak, DR. Blake, S. Meinardi, FS. Rowland, A. Pontello, DM. Cooper, PR. Galassetti
Proc. Natl. Acad. Sci. U.S.A. 2007 Oct;104(40):15613-8. PubMed:17895380
Measurement of IL-13-induced iNOS-derived gas phase nitric oxide in human bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 2007 V. Suresh, JD. Mih, SC. George
Am. J. Respir. Cell Mol. Biol. 2007 Jul;37(1):97-104. PubMed:17347445
Time-dependent effect of nitrate-rich meals on exhaled nitric oxide in healthy subjects. Chest 2005 AM. Vints, E. Oostveen, G. Eeckhaut, M. Smolders, WA. De Backer
Chest 2005 Oct;128(4):2465-70. PubMed:16236910
H. pylori infection increases levels of exhaled nitrate. Helicobacter 2005 M. Lechner, A. Karlseder, D. Niederseer, P. Lirk, A. Neher, J. Rieder, H. Tilg
Helicobacter 2005 Oct;10(5):385-90. PubMed:16181348
Local nitric oxide levels reflect the degree of allergic airway inflammation after segmental allergen challenge in asthmatics. Nitric Oxide 2005 VJ. Erpenbeck, RA. Jörres, M. Discher, H. Krentel, D. Tsikas, B. Luettig, N. Krug, JM. Hohlfeld
Nitric Oxide 2005 Sep;13(2):125-33. PubMed:16006159
Nitric oxide formation in the oropharyngeal tract: possible influence of cigarette smoking. Nitric Oxide 2004 H. Marteus, A. Mavropoulos, JP. Palm, AK. Ulfgren, J. Bergström, K. Alving
Nitric Oxide 2004 Nov;11(3):247-55. PubMed:15566971
Increased breath nitrous oxide after ingesting nitrate in patients with atrophic gastritis and partial gastrectomy. Clin. Chim. Acta 2004 T. Mitsui, T. Kondo
Clin. Chim. Acta 2004 Jul;345(1-2):129-33. PubMed:15193987
The cytotoxic effect of volatile organic compounds of the gas phase of cigarette smoke on lung epithelial cells. Free Radic. Biol. Med. 2003 AE. Pouli, DG. Hatzinikolaou, C. Piperi, A. Stavridou, MC. Psallidopoulos, JC. Stavrides
Free Radic. Biol. Med. 2003 Feb;34(3):345-55. PubMed:12543250
Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers. Eur. Respir. J. 2003 A. Soop, A. Sollevi, E. Weitzberg, JO. Lundberg, J. Palm, J. Albert
Eur. Respir. J. 2003 Apr;21(4):594-9. PubMed:12762341
Circulating and exhaled markers of nitric oxide and antioxidant activity after smoking. Circulation 2002 SL. Nuttall, HC. Routledge, S. Manney
Circulation 2002 Nov;106(20):e145-6; discussion e145-6. PubMed:12427667
Assessing nitrate metabolism in the intestinal tract by measuring breath nitric oxide and nitrous oxide, and its clinical significance. Clin. Chim. Acta 2002 T. Mitsui, T. Kondo
Clin. Chim. Acta 2002 May;319(1):57-62. PubMed:11922924
Effect of ecNOS polymorphisms and coronary artery disease upon exhaled nitric oxide. J. Mol. Med. 2002 S. Thomas, C. Bruce, A. Birkhead, L. Wang
J. Mol. Med. 2002 Mar;80(3):181-6. PubMed:11894144
Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome. Am. J. Respir. Crit. Care Med. 2001 KJ. Sullivan, N. Kissoon, LJ. Duckworth, E. Sandler, B. Freeman, E. Bayne, JE. Sylvester, JJ. Lima
Am. J. Respir. Crit. Care Med. 2001 Dec;164(12):2186-90. PubMed:11751185
Mixed exhaled nitric oxide and plasma nitrites and nitrates in newborn infants. Life Sci. 2001 P. Biban, T. Zangardi, E. Baraldi, N. Dussini, L. Chiandetti, F. Zacchello
Life Sci. 2001 May;68(25):2789-97. PubMed:11432445
Exhaled and nasal nitric oxide as a marker of pneumonia in ventilated patients. Am. J. Respir. Crit. Care Med. 2001 C. Adrie, M. Monchi, AT. Dinh-Xuan, J. Dall'Ava-Santucci, JF. Dhainaut, MR. Pinsky
Am. J. Respir. Crit. Care Med. 2001 Apr;163(5):1143-9. PubMed:11316650
Increased nitric oxide in exhaled air after intake of a nitrate-rich meal. Respir Med 2001 AC. Olin, A. Aldenbratt, A. Ekman, G. Ljungkvist, L. Jungersten, K. Alving, K. Torén
Respir Med 2001 Feb;95(2):153-8. PubMed:11217912
Estimation of nitrate metabolism in intestinal tract by measuring breath nitrous oxide concentration in Chinese and Japanese. Dig. Dis. Sci. 2000 T. Mitsui, N. Kato, T. Kondo
Dig. Dis. Sci. 2000 May;45(5):1002-5. PubMed:10795767
Association of fasting breath nitrous oxide concentration with gastric juice nitrate and nitrite concentrations and Helicobacter pylori infection. Dig. Dis. Sci. 2000 T. Kondo, T. Mitsui, M. Kitagawa, Y. Nakae
Dig. Dis. Sci. 2000 Oct;45(10):2054-7. PubMed:11117583
Relative role of heme nitrosylation and beta-cysteine 93 nitrosation in the transport and metabolism of nitric oxide by hemoglobin in the human circulation. Proc. Natl. Acad. Sci. U.S.A. 2000 MT. Gladwin, FP. Ognibene, LK. Pannell, JS. Nichols, ME. Pease-Fye, JH. Shelhamer, AN. Schechter
Proc. Natl. Acad. Sci. U.S.A. 2000 Aug;97(18):9943-8. PubMed:10954746
Effects of short-term nitrogen monoxide inhalation on leukocyte adhesion molecules, generation of reactive oxygen species, and cytokine release in human blood. Nitric Oxide 2000 H. Opdahl, T. Haugen, IA. Hagberg, T. Aspelin, T. Lyberg
Nitric Oxide 2000 Apr;4(2):112-22. PubMed:10835291
Endogenous nitric oxide in patients with chronic heart failure (CHF): relation to functional impairment and nitrate-containing therapies. Int. J. Cardiol. 2000 E. Clini, M. Volterrani, M. Pagani, L. Bianchi, R. Porta, LS. Gile', A. Giordano, N. Ambrosino
Int. J. Cardiol. 2000 Apr;73(2):123-30; discussion 131-4. PubMed:10817849
Quality of life after coronary angioplasty or continued medical treatment for angina: three-year follow-up in the RITA-2 trial. Randomized Intervention Treatment of Angina. J. Am. Coll. Cardiol. 2000 SJ. Pocock, RA. Henderson, T. Clayton, GH. Lyman, DA. Chamberlain
J. Am. Coll. Cardiol. 2000 Mar;35(4):907-14. PubMed:10732887
Non-surgical management of erectile dysfunction. Clin. Endocrinol. (Oxf) 2000 A. Levy, T. Crowley, C. Gingell
Clin. Endocrinol. (Oxf) 2000 Mar;52(3):253-60. PubMed:10718821
Body nitrosation potential measured by a novel 15N breath test. Free Radic. Biol. Med. 1999 P. Junghans, U. Fischer, B. Kuklinski
Free Radic. Biol. Med. 1999 Dec;27(11-12):1302-7. PubMed:10641724
An 18oxygen inhalation method for determination of total body formation of nitric oxide in humans. Clin Physiol 1999 A. Sakinis, L. Jungersten, A. Wennmalm
Clin Physiol 1999 Nov;19(6):504-9. PubMed:10583344
Vegetables, high nitrate foods, increased breath nitrous oxide. Dig. Dis. Sci. 1999 T. Mitsui, T. Kondo
Dig. Dis. Sci. 1999 Jun;44(6):1216-9. PubMed:10389699
Markers of nitric oxide metabolism in sputum and exhaled air are not increased in chronic obstructive pulmonary disease. Thorax 1999 SR. Rutgers, TW. van der Mark, W. Coers, H. Moshage, W. Timens, HF. Kauffman, GH. Koëter, DS. Postma
Thorax 1999 Jul;54(7):576-80. PubMed:10377200
Down-regulation of nitric oxide production by ibuprofen in human volunteers. J. Pharmacol. Exp. Ther. 1999 RW. Vandivier, A. Eidsath, SM. Banks, HL. Preas, SB. Leighton, PJ. Godin, AF. Suffredini, RL. Danner
J. Pharmacol. Exp. Ther. 1999 Jun;289(3):1398-403. PubMed:10336532
Assessment of nitric oxide formation during exercise. Am. J. Respir. Crit. Care Med. 1999 CM. St Croix, TJ. Wetter, DF. Pegelow, KC. Meyer, JA. Dempsey
Am. J. Respir. Crit. Care Med. 1999 Apr;159(4 Pt 1):1125-33. PubMed:10194156
Salivary contribution to exhaled nitric oxide. Eur. Respir. J. 1999 W. Zetterquist, C. Pedroletti, JO. Lundberg, K. Alving
Eur. Respir. J. 1999 Feb;13(2):327-33. PubMed:10065676
Increased excretion of nitric oxide in exhaled air of patients with chronic renal failure. Clin. Sci. 1999 A. Matsumoto, Y. Hirata, M. Kakoki, D. Nagata, Si. Momomura, T. Sugimoto, H. Tagawa, M. Omata
Clin. Sci. 1999 Jan;96(1):67-74. PubMed:9857108
Nasal nitric oxide and its relationship to nasal symptoms, smoking and nasal nitrate. Rhinology 1998 AC. Olin, J. Hellgren, G. Karlsson, G. Ljungkvist, K. Nolkrantz, K. Torén
Rhinology 1998 Sep;36(3):117-21. PubMed:9830675
Exhaled oral and nasal nitric oxide during L-arginine infusion in preeclampsia. Gynecol. Obstet. Invest. 1998 C. Grunewald, K. Carlström, G. Kumlien, A. Ringqvist, J. Lundberg
Gynecol. Obstet. Invest. 1998 ;46(4):232-7. PubMed:9813440
Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells. J. Clin. Invest. 1998 TJ. Kelley, ML. Drumm
J. Clin. Invest. 1998 Sep;102(6):1200-7. PubMed:9739054
Total sputum nitrate plus nitrite is raised during acute pulmonary infection in cystic fibrosis. Am. J. Respir. Crit. Care Med. 1998 SJ. Linnane, VM. Keatings, CM. Costello, JB. Moynihan, CM. O'Connor, MX. Fitzgerald, P. McLoughlin
Am. J. Respir. Crit. Care Med. 1998 Jul;158(1):207-12. PubMed:9655731
Nitrite and nitrate analyses: a clinical biochemistry perspective. Clin. Biochem. 1998 G. Ellis, I. Adatia, M. Yazdanpanah, SK. Makela
Clin. Biochem. 1998 Jun;31(4):195-220. PubMed:9646943
Nitric oxide metabolites in cystic fibrosis lung disease. Arch. Dis. Child. 1998 H. Grasemann, I. Ioannidis, RP. Tomkiewicz, H. de Groot, BK. Rubin, F. Ratjen
Arch. Dis. Child. 1998 Jan;78(1):49-53. PubMed:9534676
Drinking water and cancer. Cancer Causes Control 1997 KP. Cantor
Cancer Causes Control 1997 May;8(3):292-308. PubMed:9498894
Exhaled nitric oxide and bronchoalveolar lavage nitrite/nitrate in active pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 1997 DM. O'Donnell, J. Moynihan, GA. Finlay, VM. Keatings, CM. O'Connor, P. McLoughlin, MX. Fitzgerald
Am. J. Respir. Crit. Care Med. 1997 Dec;156(6):1892-6. PubMed:9412571
Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis. Hepatology 1997 G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca
Hepatology 1997 Oct;26(4):842-7. PubMed:9328302
Modulation of adenovirus-mediated gene transfer by nitric oxide. Am. J. Respir. Cell Mol. Biol. 1997 IY. Haddad, EJ. Sorscher, RI. Garver, J. Hong, E. Tzeng, S. Matalon
Am. J. Respir. Cell Mol. Biol. 1997 May;16(5):501-9. PubMed:9160832
The effect of the menstrual cycle on exhaled nitric oxide and urinary nitrate concentration. Eur. J. Clin. Invest. 1996 NH. Morris, SR. Sooranna, PJ. Steer, JB. Warren
Eur. J. Clin. Invest. 1996 Jun;26(6):481-4. PubMed:8817162
Sex differences in concentrations of exhaled nitric oxide and plasma nitrate. Life Sci. 1996 B. Jilma, J. Kastner, C. Mensik, B. Vondrovec, J. Hildebrandt, K. Krejcy, OF. Wagner, HG. Eichler
Life Sci. 1996 ;58(6):469-76. PubMed:8569419
L-arginine increases exhaled nitric oxide in normal human subjects. Clin. Sci. 1995 SA. Kharitonov, G. Lubec, B. Lubec, M. Hjelm, PJ. Barnes
Clin. Sci. 1995 Feb;88(2):135-9. PubMed:7720336
Asthmatic responses to airborne acid aerosols. Am J Public Health 1991 BD. Ostro, MJ. Lipsett, MB. Wiener, JC. Selner
Am J Public Health 1991 Jun;81(6):694-702. PubMed:1851397
Regional cerebral blood flow changes associated with amyl nitrite inhalation. Br J Addict 1989 RJ. Mathew, WH. Wilson, SR. Tant
Br J Addict 1989 Mar;84(3):293-99. PubMed:2706385
The influence of chemical and physical forms of ambient air acids on airway doses. Environ. Health Perspect. 1989 TV. Larson
Environ. Health Perspect. 1989 Feb;79:7-13. PubMed:2539992
Regional deposition of inhaled fog droplets: preliminary observations. Environ. Health Perspect. 1989 SM. Bowes, BL. Laube, JM. Links, R. Frank
Environ. Health Perspect. 1989 Feb;79:151-7. PubMed:2539988
Acidity potentiates bronchoconstriction induced by hypoosmolar aerosols. Am. Rev. Respir. Dis. 1988 JR. Balmes, JM. Fine, D. Christian, T. Gordon, D. Sheppard
Am. Rev. Respir. Dis. 1988 Jul;138(1):35-9. PubMed:2849338
Trichloroethylene, tetrachloroethylene, nitrates, and other chemicals in well water in the Fresno-Clovis Metropolitan Area. Arch. Environ. Health H. Kloos
Arch. Environ. Health 1997 Sep-Oct;52(5):348-54. PubMed:9546757

Associated curated diseases 4

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Associated disease mapping

Mapping of all associated diseases to nitrate is displayed in red.

Heart Lung Airway Esophagus Kidney Intestine
Disease Name

with link to disease page

Description of MeSH term

with link to MeSH Database

Number of references
Asthma MeSH: Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Link to MeSH Database: D001249
91
Cystic Fibrosis MeSH: Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION. Year introduced: 1967
Link to MeSH Database: D003550
20
Community Acquired Pneumonia MeSH: Pneumonia
Infection of the lung often accompanied by inflammation. Year introduced: 1963
Link to MeSH Database: D011014
2
Community Acquired Pneumonia MeSH: Community-Acquired Infections
Any infection acquired in the community, that is, contrasted with those acquired in a health care facility (CROSS INFECTION). An infection would be classified as community-acquired if the patient had not recently been in a health care facility or been in contact with someone who had been recently in a health care facility. Year introduced: 1994
Link to MeSH Database: D017714
2

Associated abnormalities 4

Concept Name External ID Weighted Score Hits References
Acute mountain sickness 958.0 2
  1. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
  2. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Heart failure ICD9-CM:428 1000.0 1
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
Hypertension, Pulmonary 978.26 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Brachial artery occlusion 1000.0 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide

Associated chemicals 14

Concept Name External ID Definition Weighted Score Hits References
Nitrate 955.24 28
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
  2. Exhaled nitric oxide and bronchoalveolar lavage nitrite/nitrate in active pulmonary sarcoidosis.
    DM. O'Donnell, J. Moynihan, GA. Finlay, VM. Keatings, CM. O'Connor, P. McLoughlin, MX. Fitzgerald (1997) Am. J. Respir. Crit. Care Med.
  3. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
  4. An 18oxygen inhalation method for determination of total body formation of nitric oxide in humans.
    A. Sakinis, L. Jungersten, A. Wennmalm (1999) Clin Physiol
  5. Quality of life after coronary angioplasty or continued medical treatment for angina: three-year follow-up in the RITA-2 trial. Randomized Intervention Treatment of Angina.
    SJ. Pocock, RA. Henderson, T. Clayton, GH. Lyman, DA. Chamberlain (2000) J. Am. Coll. Cardiol.
  6. Circulating and exhaled markers of nitric oxide and antioxidant activity after smoking.
    SL. Nuttall, HC. Routledge, S. Manney (2002) Circulation
  7. Nitric oxide formation in the oropharyngeal tract: possible influence of cigarette smoking.
    H. Marteus, A. Mavropoulos, JP. Palm, AK. Ulfgren, J. Bergström, K. Alving (2004) Nitric Oxide
  8. Serum nitrite and nitrate levels in children with obstructive sleep-disordered breathing.
    A. Kaditis, E. Alexopoulos, G. Ntamagka, K. Chaidas, A. Karathanasi, S. Gougoura, AA. Papathanasiou, P. Liakos, E. Zintzaras, K. Gourgoulianis (2010) Sleep Med.
  9. Diuretic, opiate and nitrate use in severe acidotic acute cardiogenic pulmonary oedema: analysis from the 3CPO trial.
    A. Gray, S. Goodacre, M. Seah, S. Tilley (2010) QJM
  10. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
  11. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
  12. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
  13. Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
    CP. Kerley, E. Kilbride, P. Greally, B. Elnazir (2016) Clin Med Res
  14. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Ammonium 984.0 9
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
  2. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
  3. Nitric oxide formation in the oropharyngeal tract: possible influence of cigarette smoking.
    H. Marteus, A. Mavropoulos, JP. Palm, AK. Ulfgren, J. Bergström, K. Alving (2004) Nitric Oxide
  4. Serum nitrite and nitrate levels in children with obstructive sleep-disordered breathing.
    A. Kaditis, E. Alexopoulos, G. Ntamagka, K. Chaidas, A. Karathanasi, S. Gougoura, AA. Papathanasiou, P. Liakos, E. Zintzaras, K. Gourgoulianis (2010) Sleep Med.
Nitrogen CHEBI:17997 924.56 8
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
  2. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
  3. A process to prepare a synthetic filter material containing nutrients for biofiltration.
    WC. Chan, ZY. Lin (2006) Bioresour. Technol.
  4. Diuretic, opiate and nitrate use in severe acidotic acute cardiogenic pulmonary oedema: analysis from the 3CPO trial.
    A. Gray, S. Goodacre, M. Seah, S. Tilley (2010) QJM
  5. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Nitrite 980.07 6
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
  2. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
  3. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
  4. Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
    CP. Kerley, E. Kilbride, P. Greally, B. Elnazir (2016) Clin Med Res
  5. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Anions 964.43 3
  1. Circulating and exhaled markers of nitric oxide and antioxidant activity after smoking.
    SL. Nuttall, HC. Routledge, S. Manney (2002) Circulation
  2. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Deuterium 734.28 3
  1. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
  2. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
NITRATE AND NITRITE 894.74 2
  1. Diuretic, opiate and nitrate use in severe acidotic acute cardiogenic pulmonary oedema: analysis from the 3CPO trial.
    A. Gray, S. Goodacre, M. Seah, S. Tilley (2010) QJM
  2. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Amides 860.67 1
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Stable isotope 1000.0 1
  1. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Superoxides CHEBI:18421 885.05 1
  1. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Protium 813.64 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Chlorides 867.94 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Molecular oxygen 933.5 1
  1. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
small molecule 1000.0 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water

Associated functions 51

Concept Name External ID Definition Weighted Score Hits References
Ingestion 958.25 9
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
  2. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
  3. Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
    CP. Kerley, E. Kilbride, P. Greally, B. Elnazir (2016) Clin Med Res
  4. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
nitrate assimilation 976.0 7
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
  2. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Oxidation 978.0 5
  1. Local nitric oxide levels reflect the degree of allergic airway inflammation after segmental allergen challenge in asthmatics.
    VJ. Erpenbeck, RA. Jörres, M. Discher, H. Krentel, D. Tsikas, B. Luettig, N. Krug, JM. Hohlfeld (2005) Nitric Oxide
  2. Diuretic, opiate and nitrate use in severe acidotic acute cardiogenic pulmonary oedema: analysis from the 3CPO trial.
    A. Gray, S. Goodacre, M. Seah, S. Tilley (2010) QJM
  3. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Hypoxia 914.6 5
  1. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
  2. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
nitrate transport GO:0015706 973.72 4
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Torque 941.83 4
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
Exhalation 827.13 4
  1. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
  2. Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
    CP. Kerley, E. Kilbride, P. Greally, B. Elnazir (2016) Clin Med Res
  3. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Regulation 964.83 4
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
  2. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Force 934.0 3
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
Contraction 914.5 3
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
  2. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Respiration 944.0 3
  1. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
  2. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
Biological Transport, Active 769.21 2
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Transcription, Genetic 795.45 2
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Adjudication 985.67 2
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Phosphorylation 895.5 2
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
  2. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
Muscle function 967.92 2
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
inhibitors 926.5 2
  1. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Synthesis 1000.0 2
  1. Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
    CP. Kerley, E. Kilbride, P. Greally, B. Elnazir (2016) Clin Med Res
  2. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
tissue oxygenation 1000.0 2
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
oxygen transport 1000.0 2
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Photosynthesis 926.5 2
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
Vasodilation 1000.0 2
  1. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
  2. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Drug Interactions 770.86 2
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
  2. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
interleukin-8 receptor binding activity 551.28 1
  1. Sex differences in concentrations of exhaled nitric oxide and plasma nitrate.
    B. Jilma, J. Kastner, C. Mensik, B. Vondrovec, J. Hildebrandt, K. Krejcy, OF. Wagner, HG. Eichler (1996) Life Sci.
interleukin-6 receptor binding activity 551.28 1
  1. Sex differences in concentrations of exhaled nitric oxide and plasma nitrate.
    B. Jilma, J. Kastner, C. Mensik, B. Vondrovec, J. Hildebrandt, K. Krejcy, OF. Wagner, HG. Eichler (1996) Life Sci.
Protein Binding GO:0005515 1000.0 1
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
protein kinase activity GO:0004672 937.5 1
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
protein N-terminus binding 766.58 1
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Post-Translational Regulation 942.0 1
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
transporter activity GO:0005215 1000.0 1
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Reverse Transcription 810.0 1
  1. Serum nitrite and nitrate levels in children with obstructive sleep-disordered breathing.
    A. Kaditis, E. Alexopoulos, G. Ntamagka, K. Chaidas, A. Karathanasi, S. Gougoura, AA. Papathanasiou, P. Liakos, E. Zintzaras, K. Gourgoulianis (2010) Sleep Med.
nitrification 1000.0 1
  1. Diuretic, opiate and nitrate use in severe acidotic acute cardiogenic pulmonary oedema: analysis from the 3CPO trial.
    A. Gray, S. Goodacre, M. Seah, S. Tilley (2010) QJM
Muscle property 1000.0 1
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
Physiological Effects 1000.0 1
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
Cytokinesis of the fertilized ovum 548.15 1
  1. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Oxidants 1000.0 1
  1. Effects of hyperbaric oxygen on nitric oxide generation in humans.
    J. Uusijärvi, K. Eriksson, AC. Larsson, C. Nihlén, T. Schiffer, P. Lindholm, E. Weitzberg (2015) Nitric Oxide
Antimicrobial Effect 970.0 1
  1. Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
    CP. Kerley, E. Kilbride, P. Greally, B. Elnazir (2016) Clin Med Res
Hypotensive 930.5 1
  1. Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
    CP. Kerley, E. Kilbride, P. Greally, B. Elnazir (2016) Clin Med Res
Pathological Dilatation 673.91 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Isometric Contraction 952.4 1
  1. Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women.
    AR. Coggan, JL. Leibowitz, A. Kadkhodayan, DP. Thomas, S. Ramamurthy, CA. Spearie, S. Waller, M. Farmer, LR. Peterson (2015) Nitric Oxide
Baresthesia 764.64 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Crossing Over, Genetic 550.77 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Alveolar ventilation function 633.66 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide
Cell Growth GO:0016049 1000.0 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
nitrite transport 1000.0 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
Signal Transduction GO:0007165 682.47 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
Cell physiology 958.17 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
Adaptation 944.0 1
  1. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
Physiologic Function 1000.0 1
  1. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
Metabolic Rates 911.67 1
  1. Effects of dietary nitrate supplementation on symptoms of acute mountain sickness and basic physiological responses in a group of male adolescents during ascent to Mount Everest Base Camp.
    PJ. Hennis, K. Mitchell, E. Gilbert-Kawai, V. Bountziouka, A. Wade, M. Feelisch, MP. Grocott, DS. Martin (2016) Nitric Oxide
Inspiration function 644.0 1
  1. Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    HG. Gasier, AR. Reinhold, AR. Loiselle, SE. Soutiere, DM. Fothergill (2017) Nitric Oxide

Associated genes 5

Concept Name External ID Definition Weighted Score Hits References
Operon 925.5 2
  1. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis.
    G. Rolla, L. Brussino, P. Colagrande, L. Dutto, S. Polizzi, E. Scappaticci, S. Bergerone, M. Morello, A. Marzano, G. Martinasso, M. Salizzoni, C. Bucca (1997) Hepatology
Genes, Essential 968.75 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
NIT2 gene EntrezGene:56954 1000.0 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
Genes, Regulator 965.2 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water
Gene Clusters 912.0 1
  1. Redox processes and water quality of selected principal aquifer systems.
    PB. McMahon, FH. Chapelle () Ground Water

Chemical Information

Formula NO3
Mass 62.004
Synonyms nitrate
NITRATE ION
14797-55-8
Nitrate(1-)
UNII-T93E9Y2844
Nitrate(6CI,7CI,8CI,9CI)
UN3218
NO3-
Nitrates
NO3
nitrooxidane
trioxidonitrate
trioxonitrate
trioxonitrate(V)
trioxonitrate(1-)
trioxidonitrate(1-)
AC1L1ADK
Nitrates, inorganic, n.o.s.
CHEMBL186200
BDBM26988
PubChem CID 943