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Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
CP. Kerley, E. Kilbride, P. Greally, B. Elnazir
Clin Med Res 2016 Dec;14(3-4):151-155.
PubMed: 27630187
Abstract
Airway nitric oxide (NO) is a ubiquitous signaling molecule with bronchoprotective, anti-inflammatory and anti-infective roles. Cystic fibrosis (CF) is a chronic lung condition associated with deceased exhaled NO. Strategies to increase exhaled NO in CF have yielded inconsistent results. A potential new method of increasing systemic NO involves ingestion of dietary, inorganic nitrate which is reduced to nitrite and NO. We present the case of a 12-year-old, athletic boy with CF who demonstrated acute but marked increases in exhaled NO following dietary nitrate consumption compared to placebo.
Associated compounds:
Compound Name
with link to compound page |
Structure | Number of references |
---|---|---|
Nitrate | 183 |