Formate
Description
Description of formate with associated disease summary
Formate is the anion derived from formic acid which is the simplest carboxylic acid. Formate is an intermediate in normal metabolism and it typically produced as a byproduct in the production of acetate. Recently, Formate was used to separate the patients with smoking-related diseases using NMR-based metabolomics of exhaled breath condensate (EBC) (J Proteome Res. (2013)). Description of disease(s) related to Formate:
Disease summary
Pulmonary Langerhans Cell Histiocytosis (PLCH)
The increase in the level of formate was found in subjects with PLCH, compared to COPD subjects.
Chronic Obstructive Pulmonary Disease (COPD)
The decrease in the level of formate was found in subjects with COPD, compared to normal and PLCH subjects.
Summary of extracted biomedical information
The involved biomedical functions are known as Adjudication, Analyte and Ingestion. formate is associated with Glycolates, Oxalates, Fumarates, Organic acid and Sulfuric Acid Esters.
Associated references with human 3
Download references|
Reference title
with link to reference page |
Journal | Year | Authors & PubMed Link |
|---|---|---|---|
| Separation of oxalate, formate and glycolate in human body fluid samples by capillary electrophoresis with contactless conductometric detection. | J Chromatogr A | 2014 |
P. Kubáň, P. Ďurč, M. Bittová, F. Foret
J Chromatogr A 2014 Jan;1325:241-6. PubMed:24388242 |
| Separating smoking-related diseases using NMR-based metabolomics of exhaled breath condensate. | J. Proteome Res. | 2013 |
G. de Laurentiis, D. Paris, D. Melck, P. Montuschi, M. Maniscalco, A. Bianco, M. Sofia, A. Motta
J. Proteome Res. 2013 Mar;12(3):1502-11. PubMed:23360153 |
| Effects of sample processing, time and storage condition on cysteinyl leukotrienes in exhaled breath condensate. | J Breath Res | 2010 |
AS. Ohanian, J. Zimmerman, JS. Debley
J Breath Res 2010 Dec;4(4):046002. PubMed:21383485 |
Associated curated diseases 1
Download diseasesAssociated disease mapping
Mapping of all associated diseases to formate is displayed in red.
|
Disease Name
with link to disease page |
Description of MeSH term
with link to MeSH Database |
Number of references |
|---|---|---|
| Chronic Obstructive Pulmonary Disease (Copd) |
MeSH:
Pulmonary Disease, Chronic Obstructive
A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
Year introduced: 2002
Link to MeSH Database: D029424
|
31 |
Associated abnormalities 0
No associated abnormalities are detected in current reference collection.
There are 3 associated references with formate. Due to lack of full text of references or no associated abnormalities are detected in our text-mining workflow, we cannot extract any abnormality terms from the associated reference collection.
Associated chemicals 0
No associated chemicals are detected in current reference collection.
There are 3 associated references with formate. Due to lack of full text of references or no associated chemicals are detected in our text-mining workflow, we cannot extract any chemical terms from the associated reference collection.
Associated functions 0
No associated functions are detected in current reference collection.
There are 3 associated references with formate. Due to lack of full text of references or no associated functions are detected in our text-mining workflow, we cannot extract any function terms from the associated reference collection.
Associated genes 0
No associated genes are detected in current reference collection.
There are 3 associated references with formate. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.
NCBI Entrez Crosslinks
Chemical Information
| Formula | CHO2 |
| Mass | 45.017 |
| Synonyms | formate Formic acid, ion(1-) HCO2 anion 71-47-6 aminate formylate methanoate hydrogen carboxylate Ammonium tetraformate CHEMBL183491 formiate Formate ion Sodium formate a carboxyl group Hydrogencarboxylic acid HCOO- AC1L18W4 GTPL4540 CHEBI:15740 CTK5I5292 |
| PubChem CID | 283 |