2-ethylhexan-1-ol

Summary of extracted biomedical information

2-ethylhexan-1-ol is associated with abnormalities such as Pleural Effusion, Malignant. The involved biomedical functions are known as volatile substances, effusion and Pleural effusion disorder. The associated genes/proteins with 2-ethylhexan-1-ol are TERT gene. 2-ethylhexan-1-ol is associated with cyclohexanone, octane, Toluene, 2-phenyl-2-propanol and Ketones.

Associated references with human 8

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Reference title

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Journal Year Authors & PubMed Link
A review of the volatiles from the healthy human body. J Breath Res 2014 B. de Lacy Costello, A. Amann, H. Al-Kateb, C. Flynn, W. Filipiak, T. Khalid, D. Osborne, NM. Ratcliffe
J Breath Res 2014 Mar;8(1):014001. PubMed:24421258
Blood volatile compounds as biomarkers for colorectal cancer. Cancer Biol. Ther. 2014 C. Wang, P. Li, A. Lian, B. Sun, X. Wang, L. Guo, C. Chi, S. Liu, W. Zhao, S. Luo, Z. Guo, Y. Zhang, C. Ke, G. Ye, G. Xu, F. Zhang, E. Li
Cancer Biol. Ther. 2014 Feb;15(2):200-6. PubMed:24100612
[Association of indoor air quality with physical health of users in a newly built school building in a university]. Nihon Eiseigaku Zasshi 2011 M. Mori, K. Hara, T. Miyakita, T. Ishitake
Nihon Eiseigaku Zasshi 2011 Jan;66(1):122-8. PubMed:21358143
Acute effects of exposure to 1 mg/m(3) of vaporized 2-ethyl-1-hexanol in humans. Indoor Air 2010 L. Ernstgård, D. Norbäck, T. Nordquist, G. Wieslander, R. Wålinder, G. Johanson
Indoor Air 2010 Apr;20(2):168-75. PubMed:20409194
Annual transition and seasonal variation of indoor air pollution levels of 2-ethyl-1-hexanol in large-scale buildings in Nagoya, Japan. J Environ Monit 2009 K. Sakai, M. Kamijima, E. Shibata, H. Ohno, T. Nakajima
J Environ Monit 2009 Nov;11(11):2068-76. PubMed:19890564
[Investigation of air pollution in a shopping center and employees' personal exposure level]. Nihon Eiseigaku Zasshi 2008 R. Manabe, N. Kunugita, T. Katoh, Y. Kuroda, Y. Akiyama, Y. Yamano, I. Uchiyama, K. Arashidani
Nihon Eiseigaku Zasshi 2008 Jan;63(1):20-8. PubMed:18306654
Experimental PVC material challenge in subjects with occupational PVC exposure. Environ. Health Perspect. 2006 A. Tuomainen, H. Stark, M. Seuri, MR. Hirvonen, M. Linnainmaa, A. Sieppi, H. Tukiainen
Environ. Health Perspect. 2006 Sep;114(9):1409-13. PubMed:16966097
Nasal lavage biomarkers: effects of water damage and microbial growth in an office building. Arch. Environ. Health R. Wålinder, D. Norbäck, B. Wessen, P. Venge
Arch. Environ. Health 2001 Jan-Feb;56(1):30-6. PubMed:11256854

Associated curated diseases 3

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Associated disease mapping

Mapping of all associated diseases to 2-ethylhexan-1-ol is displayed in red.

Heart Lung Airway Esophagus Kidney Intestine
Disease Name

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Description of MeSH term

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Number of references
Chronic Obstructive Pulmonary Disease (Copd) MeSH: Pulmonary Disease, Chronic Obstructive
A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA. Year introduced: 2002
Link to MeSH Database: D029424
31
Bronchiectasis MeSH: Bronchiectasis
Persistent abnormal dilatation of the bronchi.
Link to MeSH Database: D001987
3
Asthma MeSH: Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Link to MeSH Database: D001249
91

Associated abnormalities 1

Concept Name External ID Weighted Score Hits References
Pleural Effusion, Malignant ICD9-CM:511.81 1000.0 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.

Associated chemicals 10

Concept Name External ID Definition Weighted Score Hits References
cyclohexanone 1000.0 3
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
octane 1000.0 2
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
Toluene CHEBI:17578 1000.0 2
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
2-phenyl-2-propanol 1000.0 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
Ketones CHEBI:17087 1000.0 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
2-methylnaphthalene 1000.0 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
n-dodecane 900.0 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
decane 1000.0 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
Phenols CHEBI:33853 928.57 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
n-hexanal 888.89 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.

Associated functions 3

Concept Name External ID Definition Weighted Score Hits References
volatile substances 899.68 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
effusion 1000.0 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
Pleural effusion disorder 815.25 1
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.

Associated genes 1

Concept Name External ID Definition Weighted Score Hits References
TERT gene EntrezGene:7015 722.22 2
  1. Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry.
    H. Liu, H. Wang, C. Li, L. Wang, Z. Pan, L. Wang (2014) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.

Chemical Information

Formula C8H18O
Mass 130.231
Synonyms 2-Ethylhexan-1-ol
2-Ethylhexanol
2-ETHYL-1-HEXANOL
104-76-7
1-Hexanol, 2-ethyl-
2-Ethylhexyl alcohol
Ethylhexanol
Alcohol, 2-ethylhexyl
xi-2-Ethyl-1-hexanol
2-Aethylhexanol [German]
Ethylhexanol, 2-
FEMA No. 3151
CCRIS 2292
HSDB 1118
NSC 9300
EINECS 203-234-3
BRN 1719280
AI3-00940
CHEBI:16011
YIWUKEYIRIRTPP-UHFFFAOYSA-N
DSSTox_CID_605
DSSTox_RID_75686
DSSTox_GSID_20605
2-Aethylhexanol
CAS-104-76-7
Exxal 8N
2-ETHYL HEXANOL
1-Hexanol, 2-ethyl-, (S)-
2-ethyhexanol
2 Ethylhexanol
2-ethyl-hexanol
2-ethylhexylalcohol
EINECS 295-250-2
Alcohols, C7-9-branched, C8-rich
2-ethyl 1-hexanol
2-ethyl hexyl alcohol
2-Ethyl-hexan-1-ol
ACMC-20msz8
AC1L1PEC
EC 203-234-3
AC1Q2V9L
AC1Q7BK8
ACMC-1B65F
SCHEMBL16324
4-01-00-01783 (Beilstein Handbook Reference)
KSC175S7B
MLS002415694
CHEMBL31637
DTXSID5020605
2-Ethyl-1-hexanol, >=99%
CTK0H5970
FEMA 3151
Alcohols, C7-9-iso-,C8-rich
NSC9300
MolPort-001-787-201
HMS2268N10
WLN: Q1Y4 & 2
128821-84-1
NSC-9300
2-Ethyl-1-hexanol, >=99.6%
Tox21_202071
Tox21_300019
ANW-15107
LMFA05000703
LS-380
SBB059906
STL453673
2-Ethyl-1-hexanol, >=99%, FG
2-Ethyl-1-hexanol, 99% 500ml
AKOS000120105
AKOS016843836
MCULE-1768780358
RTR-001032
TRA0052020
1070-10-6 (titanium(4+) salt)
2-Ethyl-1-hexanol, analytical standard
NCGC00091294-01
NCGC00091294-02
NCGC00091294-03
NCGC00254215-01
NCGC00259620-01
L260
SMR000112222
KB-170355
TR-001032
E0122
FT-0612231
FT-0627437
ST24040552
ST51046173
C02498
2-Ethyl-1-hexanol, puriss., >=99.0% (GC)
33017-EP2305033A1
33017-EP2311815A1
33017-EP2371805A1
33017-EP2377844A2
2-Ethyl-1-hexanol, SAJ first grade, >=99.0%
W-109057
I14-17807
2-Ethylhexan-1-ol, United States Pharmacopeia (USP) Reference Standard
InChI=1/C8H18O/c1-3-5-6-8(4-2)7-9/h8-9H,3-7H2,1-2H
111675-57-1
PubChem CID 7720