Methanedithione

Summary of extracted biomedical information

Methanedithione is associated with abnormalities such as Gastroesophageal reflux disease. The involved biomedical functions are known as Adjudication and Analyte. Methanedithione is associated with acetonitrile, isoprene, 1-Heptene, pentane and dimethyl sulfide.

Associated references with human 16

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Journal Year Authors & PubMed Link
Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study. Gastrointest. Endosc. 2016 A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik
Gastrointest. Endosc. 2016 Oct;84(4):597-603. PubMed:26646671
A review of the volatiles from the healthy human body. J Breath Res 2014 B. de Lacy Costello, A. Amann, H. Al-Kateb, C. Flynn, W. Filipiak, T. Khalid, D. Osborne, NM. Ratcliffe
J Breath Res 2014 Mar;8(1):014001. PubMed:24421258
Determination of exposure of dispensary drug preparers to cyclophosphamide by passive sampling and liquid chromatography with tandem mass spectrometry. J Oncol Pharm Pract 2013 N. Wakui, T. Ookubo, Y. Iwasaki, R. Ito, M. Mitui, Y. Yano, K. Saito, H. Nakazawa
J Oncol Pharm Pract 2013 Mar;19(1):31-7. PubMed:22753612
Could houseplants improve indoor air quality in schools? J. Toxicol. Environ. Health Part A 2012 PN. Pegas, CA. Alves, T. Nunes, EF. Bate-Epey, M. Evtyugina, CA. Pio
J. Toxicol. Environ. Health Part A 2012 ;75(22-23):1371-80. PubMed:23095155
Colorectal cancer screening with odour material by canine scent detection. Gut 2011 H. Sonoda, S. Kohnoe, T. Yamazato, Y. Satoh, G. Morizono, K. Shikata, M. Morita, A. Watanabe, M. Morita, Y. Kakeji, F. Inoue, Y. Maehara
Gut 2011 Jun;60(6):814-9. PubMed:21282130
Laser spectroscopy on volatile sulfur compounds: possibilities for breath analysis. J Breath Res 2011 L. Ciaffoni, R. Peverall, GA. Ritchie
J Breath Res 2011 Jun;5(2):024002. PubMed:21593551
Evaporative gasoline emissions and asthma symptoms. Int J Environ Res Public Health 2010 ME. Gordian, AW. Stewart, SS. Morris
Int J Environ Res Public Health 2010 08;7(8):3051-62. PubMed:20948946
Biological exposure assessment to tetrachloroethylene for workers in the dry cleaning industry. Environ Health 2008 LT. McKernan, AM. Ruder, MR. Petersen, MJ. Hein, CL. Forrester, WT. Sanderson, DL. Ashley, MA. Butler
Environ Health 2008 Apr;7:12. PubMed:18412959
Increased pentane and carbon disulfide in the breath of patients with schizophrenia. J. Clin. Pathol. 1993 M. Phillips, M. Sabas, J. Greenberg
J. Clin. Pathol. 1993 Sep;46(9):861-4. PubMed:8227439
Special nerve functions and colour discrimination in workers with long term low level exposure to carbon disulphide. Br J Ind Med 1990 MW. Ruijten, HJ. Sallé, MM. Verberk, H. Muijser
Br J Ind Med 1990 Sep;47(9):589-95. PubMed:2207029
Evaluation of occupational exposure to carbon disulphide by blood, exhaled air, and urine analysis. Am. J. Ind. Med. 1985 L. Campbell, AH. Jones, HK. Wilson
Am. J. Ind. Med. 1985 ;8(2):143-53. PubMed:4050795
Elimination kinetics of disulfiram in alcoholics after single and repeated doses. Clin. Pharmacol. Ther. 1984 MD. Faiman, JC. Jensen, RB. Lacoursiere
Clin. Pharmacol. Ther. 1984 Oct;36(4):520-6. PubMed:6090051
Assessing disulfiram compliance: validational study of an abbreviated breath test procedure. Addict Behav 1983 RG. Rychtarik, PO. Smith, SL. Jones, L. Doerfler, R. Hale, DM. Prue
Addict Behav 1983 ;8(4):361-8. PubMed:6677076
Elimination characteristics of disulfiram over time in five alcoholic volunteers: a preliminary study. Am J Psychiatry 1982 JC. Jensen, MD. Faiman, A. Hurwitz
Am J Psychiatry 1982 Dec;139(12):1596-8. PubMed:6293320
Methods for detecting disulfiram in biologic fluids: application in studies of compliance and effect of divalent cations on bioavailability. Alcohol. Clin. Exp. Res. 1978 WK. Rogers, KM. Wilson, CE. Becker
Alcohol. Clin. Exp. Res. 1978 Oct;2(4):375-80. PubMed:216281
Proceedings: The determination of disulfiram in blood, and of exhaled carbon disulphide using cathode ray polarography. J. Pharm. Pharmacol. 1974 MW. Brown, GS. Porter, AE. Williams
J. Pharm. Pharmacol. 1974 Dec;26 Suppl:95P-96P. PubMed:4156780

Associated curated diseases 0

No curated diseases are identified in current reference collection.

Associated abnormalities 1

Concept Name External ID Weighted Score Hits References
Gastroesophageal reflux disease 564.52 1
  1. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.

Associated chemicals 9

Concept Name External ID Definition Weighted Score Hits References
acetonitrile 982.63 3
  1. Determination of nicotine, tar, volatile organic compounds and carbonyls in mainstream cigarette smoke using a glass filter and a sorbent cartridge followed by the two-phase/one-pot elution method with carbon disulfide and methanol.
    S. Uchiyama, H. Hayashida, R. Izu, Y. Inaba, H. Nakagome, N. Kunugita (2015) J Chromatogr A
  2. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.
isoprene CHEBI:35194 1000.0 3
  1. Determination of nicotine, tar, volatile organic compounds and carbonyls in mainstream cigarette smoke using a glass filter and a sorbent cartridge followed by the two-phase/one-pot elution method with carbon disulfide and methanol.
    S. Uchiyama, H. Hayashida, R. Izu, Y. Inaba, H. Nakagome, N. Kunugita (2015) J Chromatogr A
  2. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.
1-Heptene 1000.0 2
  1. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.
pentane 1000.0 2
  1. Increased pentane and carbon disulfide in the breath of patients with schizophrenia.
    M. Phillips, M. Sabas, J. Greenberg (1993) J. Clin. Pathol.
  2. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.
dimethyl sulfide 1000.0 1
  1. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.
Acetaldehyde CHEBI:15343 1000.0 1
  1. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.
carbonyl compound 1000.0 1
  1. Determination of nicotine, tar, volatile organic compounds and carbonyls in mainstream cigarette smoke using a glass filter and a sorbent cartridge followed by the two-phase/one-pot elution method with carbon disulfide and methanol.
    S. Uchiyama, H. Hayashida, R. Izu, Y. Inaba, H. Nakagome, N. Kunugita (2015) J Chromatogr A
Toluene CHEBI:17578 1000.0 1
  1. Determination of nicotine, tar, volatile organic compounds and carbonyls in mainstream cigarette smoke using a glass filter and a sorbent cartridge followed by the two-phase/one-pot elution method with carbon disulfide and methanol.
    S. Uchiyama, H. Hayashida, R. Izu, Y. Inaba, H. Nakagome, N. Kunugita (2015) J Chromatogr A
Amines CHEBI:32952 847.17 1
  1. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.

Associated functions 2

Concept Name External ID Definition Weighted Score Hits References
Adjudication 985.67 1
  1. Determination of nicotine, tar, volatile organic compounds and carbonyls in mainstream cigarette smoke using a glass filter and a sorbent cartridge followed by the two-phase/one-pot elution method with carbon disulfide and methanol.
    S. Uchiyama, H. Hayashida, R. Izu, Y. Inaba, H. Nakagome, N. Kunugita (2015) J Chromatogr A
Analyte 967.93 1
  1. Volatile organic compounds in plasma for the diagnosis of esophageal adenocarcinoma: a pilot study.
    A. Bhatt, MA. Parsi, T. Stevens, S. Gabbard, A. Kumaravel, S. Jang, D. Grove, R. Lopez, S. Murthy, JJ. Vargo, R. Dweik (2016) Gastrointest. Endosc.

Associated genes 0

No associated genes are detected in current reference collection.

There are 16 associated references with Methanedithione. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.

Chemical Information

Formula CS2
Mass 76.131
Synonyms CARBON DISULFIDE
Carbon disulphide
Carbon bisulfide
75-15-0
Dithiocarbonic anhydride
Carbon bisulphide
Schwefelkohlenstoff
Weeviltox
Wegla dwusiarczek
methanedithione
Solfuro di carbonio
Carbondisulphide
Sulphocarbonic anhydride
Sulphuret of carbon
RCRA waste number P022
Caswell No. 162
disulfidocarbon
Carbon disulfide cation
Koolstofdisulfide (zwavelkoolstof)
Carbon bisulfuret
NCI-C04591
Alcohol of sulfur
Kohlendisulfid (schwefelkohlenstoff)
Wegla dwusiarczek [Polish]
Schwefelkohlenstoff [German]
Carbon disulfide [BSI:ISO]
HSDB 52
UNII-S54S8B99E8
Solfuro di carbonio [Italian]
UN 1131
CCRIS 5570
Carbone (sulfure de) [French]
Carbone (sulfuro di)
Sulfocarbonic anhydride
Carbonio (solfuro di) [Italian]
Sulfure de carbone [ISO-French]
Carbon sulfide (CS2)
EINECS 200-843-6
UN1131
RCRA waste no. P022
EPA Pesticide Chemical Code 016401
BRN 1098293
Carbon disulfide, ACS reagent
Koolstofdisulfide (zwavelkoolstof) [Dutch]
AI3-08935
Kohlendisulfid (schwefelkohlenstoff) [German]
CHEBI:23012
QGJOPFRUJISHPQ-UHFFFAOYSA-N
S54S8B99E8
NCGC00091108-01
DSSTox_CID_3947
DSSTox_RID_77238
DSSTox_GSID_23947
12539-80-9
CAS-75-15-0
Sulfure de carbone
Carbon disulfide, ACS reagent, >=99.9%
CARBONDISULFIDE
Carbone (sulfure de)
Carbonio (solfuro di)
Carbon disulfide, puriss., low in benzene, >=99.5% (GC)
Dithioxomethane
Kohlendisulfid
Carbon sulphide
Koolstofdisulfide
carbon-disulphide
Weevil-Tox
Dithioxomethane #
Carbon-disulphide-
Carbon disulfide, CP
Carbon disulphide, BSI
ACMC-20ali2
AC1L1MBX
AC1Q7EYQ
EC 200-843-6
4-03-00-00395 (Beilstein Handbook Reference)
KSC377M2H
CHEMBL1365180
DTXSID6023947
CTK2H7623
MolPort-001-768-563
Carbon disulfide, p.a., 99.5%
KS-00000X0U
Tox21_111082
Tox21_201168
Carbon disulfide, anhydrous, >=99%
AKOS009075983
LS-1657
RP18362
RTR-024207
Carbon disulfide solution, 5 M in THF
NCGC00091108-02
NCGC00258720-01
300030XA
AN-23840
Carbon disulfide, for HPLC, >=99.9%
Carbondisulfide 10 microg/mL in Methanol
Carbon disulfide, purum, >=99.0% (GC)
TR-024207
C1955
Carbon disulfide, HPLC, 99.8% min. 1L
Carbon-12C disulfide, 99.9 atom % 12C
FT-0083177
FT-0623475
Carbon disulfide, puriss., >=99.5% (GC)
Carbondisulfide, 5000 microg/mL in Methanol
C19033
Carbon disulfide [UN1131] [Flammable liquid]
Carbon disulfide, SAJ first grade, >=98.0%
Carbon disulfide [UN1131] [Flammable liquid]
Carbon disulfide, JIS special grade, >=99.0%
300030X
Carbon disulfide, spectrophotometric grade, >=99%
Carbon disulfide, puriss. p.a., >=99.9% (GC)
I14-19641
Carbon disulfide, ReagentPlus(R), low benzene, >=99.9%
Carbon disulfide solution, 5000 mug/mL in methanol, analytical standard
Carbon disulfide, ReagentPlus(R), purified by redistillation, >=99.9%
Carbon disulfide solution, certified reference material, 5000 mug/mL in methanol
355120-85-3
Carbon disulfide, for IR spectroscopy, puriss. p.a., ACS reagent, reag. Ph. Eur., >=99.9% (GC)
PubChem CID 6348