D-Glucose
Description
Description of D-Glucose with associated disease summary
In humans,
glucose concentrations are normally elevated by inflammation or hyperglycemia. Elevated
bronchial glucose is associated with increased respiratory infection in
intensive care patients.
To determine
the effects of hyperglycemia and lung disease on lung glucose concentrations,
one study recruited healthy volunteers and patients with Type 1 or 2 diabetes
mellitus, all nonsmokers and with no history of lung diseases.
G
lucose was measured by chromatography with pulsed amperometric
detection. This study finds that breath glucose in healthy volunteers was reproducible
and unaffected by changes in salivary glucose. Breath glucose was elevated in
diabetic patients without lung disease in proportion to hyperglycemia. Breath
glucose was elevated more than expected for blood glucose in cystic fibrosis (CF)
patients and in CF-related diabetes.
The noninvasive
method for glucose detection simplified the diagnosis for patients. Glucose as
a biomarker will aid in the investigations of elevated respiratory fluid
glucose in human lung diseases ( J Appl Physiol (1985).(2007)
).
Description of disease(s) related to glucose:
Diabetes Mellitus
Breath glucose was elevated in diabetic patients without lung disease in proportion to hyperglycemia (J Appl Physiol (1985).(2007) ).Cystic Fibrosis
Breath glucose was elevated in diabetic patients without lung disease in proportion to hyperglycemia. Breath glucose was elevated more than expected for blood glucose in cystic fibrosis (CF) patients and in CF-related diabetes (J Appl Physiol (1985).(2007) ).Summary of extracted biomedical information
D-glucose is associated with abnormalities such as Diabetes, Obesity, Hyperinsulinism, Dyslipidemias and Obesity, Morbid. The involved biomedical functions are known as insulin sensitivity, glucose metabolism, Insulin Resistance, Infiltration and GLUCOSE TOLERANCE. D-glucose is associated with Blood Glucose.
Associated references with human 15
Download references|
Reference title
with link to reference page |
Journal | Year | Authors & PubMed Link |
|---|---|---|---|
| Clinical assessment of the lag-time and tmax of pellets with controlled release of glucose: in vitro/in vivo comparison using 13 C-breath test. | Biopharm Drug Dispos | 2017 |
D. Neumann, J. Muselík, D. Sabadková, S. Pavloková, J. Špirková, A. Franc
Biopharm Drug Dispos 2017 Nov;38(8):458-463. PubMed:28670738 |
| Breath gas monitoring during a glucose challenge by a combined PTR-QMS/GC×GC-TOFMS approach for the verification of potential volatile biomarkers. | J Breath Res | 2016 |
B. Gruber, S. Keller, T. Groeger, G. Matuschek, W. Szymczak, R. Zimmermann
J Breath Res 2016 06;10(3):036003. PubMed:27341456 |
| Insulin sensitivity index (ISI0, 120) potentially linked to carbon isotopes of breath CO2 for pre-diabetes and type 2 diabetes. | Sci Rep | 2015 |
C. Ghosh, P. Mukhopadhyay, S. Ghosh, M. Pradhan
Sci Rep 2015 Jul;5:11959. PubMed:26148706 |
| Non-invasive 13C-glucose breath test using residual gas analyzer-mass spectrometry: a novel tool for screening individuals with pre-diabetes and type 2 diabetes. | J Breath Res | 2014 |
C. Ghosh, A. Maity, GD. Banik, S. Som, A. Chakraborty, C. Selvan, S. Ghosh, B. Ghosh, S. Chowdhury, M. Pradhan
J Breath Res 2014 Sep;8(3):036001. PubMed:24946152 |
| Current understandings and perspectives on non-cancer health effects of benzene: a global concern. | Toxicol. Appl. Pharmacol. | 2014 |
H. Bahadar, S. Mostafalou, M. Abdollahi
Toxicol. Appl. Pharmacol. 2014 Apr;276(2):83-94. PubMed:24589379 |
| [13C]glucose breath testing provides a noninvasive measure of insulin resistance: calibration analyses against clamp studies. | Diabetes Technol. Ther. | 2014 |
M. Hussain, M. Jangorbhani, S. Schuette, RV. Considine, RL. Chisholm, KJ. Mather
Diabetes Technol. Ther. 2014 Feb;16(2):102-12. PubMed:24116833 |
| Noninvasive monitoring of glucose levels: is exhaled breath the answer? | J Diabetes Sci Technol | 2012 |
K. Roberts, A. Jaffe, C. Verge, PS. Thomas
J Diabetes Sci Technol 2012 May;6(3):659-64. PubMed:22768898 |
| Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia. | BMC Med Res Methodol | 2010 |
DZ. Levett, DS. Martin, MH. Wilson, K. Mitchell, S. Dhillon, F. Rigat, HE. Montgomery, MG. Mythen, MP. Grocott, .
BMC Med Res Methodol 2010 Oct;10:98. PubMed:20964858 |
| Aluminum gallium nitride (GaN)/GaN high electron mobility transistor-based sensors for glucose detection in exhaled breath condensate. | J Diabetes Sci Technol | 2010 |
BH. Chu, BS. Kang, SC. Hung, KH. Chen, F. Ren, A. Sciullo, BP. Gila, SJ. Pearton
J Diabetes Sci Technol 2010 Jan;4(1):171-9. PubMed:20167182 |
| Nitric oxide gas phase release in human small airway epithelial cells. | Respir. Res. | 2009 |
J. Jiang, N. Malavia, V. Suresh, SC. George
Respir. Res. 2009 Jan;10:3. PubMed:19152703 |
| Influenza virus in human exhaled breath: an observational study. | PLoS ONE | 2008 |
P. Fabian, JJ. McDevitt, WH. DeHaan, RO. Fung, BJ. Cowling, KH. Chan, GM. Leung, DK. Milton
PLoS ONE 2008 Jul;3(7):e2691. PubMed:18628983 |
| NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines. | Br. J. Cancer | 2006 |
Y. Yang, T. Ikezoe, C. Nishioka, K. Bandobashi, T. Takeuchi, Y. Adachi, M. Kobayashi, S. Takeuchi, HP. Koeffler, H. Taguchi
Br. J. Cancer 2006 Dec;95(12):1653-62. PubMed:17133272 |
| Exhaled breath condensates: a potential novel technique for detecting aspiration. | Am. J. Med. | 2003 |
RM. Effros, M. Bosbous, B. Foss, R. Shaker, J. Biller
Am. J. Med. 2003 Aug;115 Suppl 3A:137S-143S. PubMed:12928090 |
| Microbiological and fermentation characteristics of togwa, a Tanzanian fermented food. | Int. J. Food Microbiol. | 2003 |
JK. Mugula, SA. Nnko, JA. Narvhus, T. Sørhaug
Int. J. Food Microbiol. 2003 Feb;80(3):187-99. PubMed:12423921 |
| Effect of codeine and loperamide on upper intestinal transit and absorption in normal subjects and patients with postvagotomy diarrhoea. | Gut | 1988 |
JD. O'Brien, DG. Thompson, A. McIntyre, WR. Burnham, E. Walker
Gut 1988 Mar;29(3):312-8. PubMed:3356363 |
Associated curated diseases 2
Download diseasesAssociated disease mapping
Mapping of all associated diseases to D-Glucose is displayed in red.
|
Disease Name
with link to disease page |
Description of MeSH term
with link to MeSH Database |
Number of references |
|---|---|---|
| Cystic Fibrosis |
MeSH:
Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE
REGULATOR expressed in several organs including the LUNG, the PANCREAS, the
BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by
epithelial secretory dysfunction associated with ductal obstruction resulting in
AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY;
maldigestion; salt depletion; and HEAT PROSTRATION.
Year introduced: 1967
Link to MeSH Database: D003550
|
20 |
| Cystic Fibrosis Related Diabetes (Cfrd) |
MeSH:
Diabetes Mellitus
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Link to MeSH Database: D003920
|
1 |
Associated abnormalities 5
Associated chemicals 0
No associated chemicals are detected in current reference collection.
There are 15 associated references with D-Glucose. Due to lack of full text of references or no associated chemicals are detected in our text-mining workflow, we cannot extract any chemical terms from the associated reference collection.
Associated functions 11
Associated genes 0
No associated genes are detected in current reference collection.
There are 15 associated references with D-Glucose. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.
NCBI Entrez Crosslinks
Chemical Information
| Formula | C6H12O6 |
| Mass | 180.156 |
| Synonyms | D-Glucose D-Glucopyranose Glucose Glucopyranose Grape sugar D-Glc Glucodin Meritose Clintose L CPC hydrate Roferose ST Clearsweet 95 Staleydex 95M D-Glcp CHEBI:4167 2280-44-6 Glucopyranoside D-Glucopyranoside Glucopyranose, D- Glc |
| PubChem CID | 5793 |