Styrene

Summary of extracted biomedical information

Styrene is associated with abnormalities such as Tangier Disease. The involved biomedical functions are known as catalyst, Pressure- physical agent, Infiltration, Inspiration function and Exocytosis. The associated genes/proteins with Styrene are MERTK gene. Styrene is associated with styrene oxide, Carbon, metal oxide, Epoxy Compounds and Sulfhydryl Compounds.
Imgsrv

Associated references with human 11

Download references
Reference title

with link to reference page

Journal Year Authors & PubMed Link
A review of the volatiles from the healthy human body. J Breath Res 2014 B. de Lacy Costello, A. Amann, H. Al-Kateb, C. Flynn, W. Filipiak, T. Khalid, D. Osborne, NM. Ratcliffe
J Breath Res 2014 Mar;8(1):014001. PubMed:24421258
Perinatal exposure to hazardous air pollutants and autism spectrum disorders at age 8. Epidemiology 2010 AE. Kalkbrenner, JL. Daniels, JC. Chen, C. Poole, M. Emch, J. Morrissey
Epidemiology 2010 Sep;21(5):631-41. PubMed:20562626
Proteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanism. Proteomics 2009 N. Mörbt, I. Mögel, S. Kalkhof, R. Feltens, C. Röder-Stolinski, J. Zheng, C. Vogt, I. Lehmann, M. von Bergen
Proteomics 2009 Nov;9(21):4920-33. PubMed:19862763
Cognitive impairment and olfactory panic from occupational exposure to VOCs. Am. J. Ind. Med. 2006 A. Reinhartz
Am. J. Ind. Med. 2006 Oct;49(10):862-4. PubMed:16960889
T(H1)-directed modulation of in vitro cytokine production in human peripheral blood mononuclear cells by styrene-7.8-oxide. Toxicol. Lett. 2006 GH. Merker, G. Metzner, F. Raabe
Toxicol. Lett. 2006 Jan;160(2):105-11. PubMed:16111840
Internal exposure of children by simulated acute inhalation of volatile organic compounds: the influence of chemical properties on the child/adult concentration ratio. Basic Clin. Pharmacol. Toxicol. 2005 K. Abraham, H. Mielke, W. Huisinga, U. Gundert-Remy
Basic Clin. Pharmacol. Toxicol. 2005 Mar;96(3):242-3. PubMed:15733221
Personal, indoor, and outdoor VOC exposures in a probability sample of children. J Expo Anal Environ Epidemiol 2004 JL. Adgate, LE. Eberly, C. Stroebel, ED. Pellizzari, K. Sexton
J Expo Anal Environ Epidemiol 2004 ;14 Suppl 1:S4-S13. PubMed:15118740
Risk assessment of exposure to volatile organic compounds in different indoor environments. Environ. Res. 2004 H. Guo, SC. Lee, LY. Chan, WM. Li
Environ. Res. 2004 Jan;94(1):57-66. PubMed:14643287
Measurement of volatile organic compounds inside automobiles. J Expo Anal Environ Epidemiol 2003 MJ. Fedoruk, BD. Kerger
J Expo Anal Environ Epidemiol 2003 Jan;13(1):31-41. PubMed:12595882
Aggression in boat builders: a search for altered mood states in boat builders exposed to styrene. Occup Med (Lond) 2000 J. Challenor, D. Wright
Occup Med (Lond) 2000 Apr;50(3):185-92. PubMed:10912362
Passive smoking, excretion of metabolites, and health effects: results of the Leipzig's Allergy Risk Study (LARS). Arch. Environ. Health UE. Rolle-Kampczyk, M. Rehwagen, U. Diez, M. Richter, O. Herbarth, M. Borte
Arch. Environ. Health 2002 Jul-Aug;57(4):326-31. PubMed:12530599

Associated curated diseases 0

No curated diseases are identified in current reference collection.

Associated abnormalities 1

Concept Name External ID Weighted Score Hits References
Tangier Disease 547.33 1
  1. T(H1)-directed modulation of in vitro cytokine production in human peripheral blood mononuclear cells by styrene-7.8-oxide.
    GH. Merker, G. Metzner, F. Raabe (2006) Toxicol. Lett.

Associated chemicals 8

Concept Name External ID Definition Weighted Score Hits References
styrene oxide CHEBI:17907 1000.0 2
  1. T(H1)-directed modulation of in vitro cytokine production in human peripheral blood mononuclear cells by styrene-7.8-oxide.
    GH. Merker, G. Metzner, F. Raabe (2006) Toxicol. Lett.
Carbon CHEBI:33415 906.83 2
  1. A biofilter integrated with gas membrane separation unit for the treatment of fluctuating styrene loads.
    L. Li, J. Lian, Y. Han, J. Liu (2012) Bioresour. Technol.
metal oxide 950.5 1
  1. The kinetics of catalytic incineration of styrene over a MnO/Fe2O3 catalyst.
    TK. Tseng, H. Chu (2001) Sci. Total Environ.
Epoxy Compounds 580.33 1
  1. T(H1)-directed modulation of in vitro cytokine production in human peripheral blood mononuclear cells by styrene-7.8-oxide.
    GH. Merker, G. Metzner, F. Raabe (2006) Toxicol. Lett.
Sulfhydryl Compounds 537.75 1
  1. Long-term operation of submerged membrane bioreactor (MBR) for the treatment of synthetic wastewater containing styrene as volatile organic compound (VOC): Effect of hydraulic retention time (HRT).
    N. Fallah, B. Bonakdarpour, B. Nasernejad, MR. Alavi Moghadam (2010) J. Hazard. Mater.
isoprene CHEBI:35194 811.5 1
  1. Long-term operation of submerged membrane bioreactor (MBR) for the treatment of synthetic wastewater containing styrene as volatile organic compound (VOC): Effect of hydraulic retention time (HRT).
    N. Fallah, B. Bonakdarpour, B. Nasernejad, MR. Alavi Moghadam (2010) J. Hazard. Mater.
Butadiene 925.5 1
  1. Long-term operation of submerged membrane bioreactor (MBR) for the treatment of synthetic wastewater containing styrene as volatile organic compound (VOC): Effect of hydraulic retention time (HRT).
    N. Fallah, B. Bonakdarpour, B. Nasernejad, MR. Alavi Moghadam (2010) J. Hazard. Mater.
Protium 1000.0 1
  1. A biofilter integrated with gas membrane separation unit for the treatment of fluctuating styrene loads.
    L. Li, J. Lian, Y. Han, J. Liu (2012) Bioresour. Technol.

Associated functions 9

Concept Name External ID Definition Weighted Score Hits References
catalyst 938.38 2
  1. The kinetics of catalytic incineration of styrene over a MnO/Fe2O3 catalyst.
    TK. Tseng, H. Chu (2001) Sci. Total Environ.
Pressure- physical agent 602.67 2
  1. A biofilter integrated with gas membrane separation unit for the treatment of fluctuating styrene loads.
    L. Li, J. Lian, Y. Han, J. Liu (2012) Bioresour. Technol.
Infiltration 1000.0 1
  1. Risk assessment of exposure to volatile organic compounds in different indoor environments.
    H. Guo, SC. Lee, LY. Chan, WM. Li (2004) Environ. Res.
Inspiration function 750.0 1
  1. T(H1)-directed modulation of in vitro cytokine production in human peripheral blood mononuclear cells by styrene-7.8-oxide.
    GH. Merker, G. Metzner, F. Raabe (2006) Toxicol. Lett.
Exocytosis GO:0006887 894.0 1
  1. T(H1)-directed modulation of in vitro cytokine production in human peripheral blood mononuclear cells by styrene-7.8-oxide.
    GH. Merker, G. Metzner, F. Raabe (2006) Toxicol. Lett.
Shock 847.0 1
  1. Long-term operation of submerged membrane bioreactor (MBR) for the treatment of synthetic wastewater containing styrene as volatile organic compound (VOC): Effect of hydraulic retention time (HRT).
    N. Fallah, B. Bonakdarpour, B. Nasernejad, MR. Alavi Moghadam (2010) J. Hazard. Mater.
flocculation 830.0 1
  1. Long-term operation of submerged membrane bioreactor (MBR) for the treatment of synthetic wastewater containing styrene as volatile organic compound (VOC): Effect of hydraulic retention time (HRT).
    N. Fallah, B. Bonakdarpour, B. Nasernejad, MR. Alavi Moghadam (2010) J. Hazard. Mater.
ionization 925.5 1
  1. Long-term operation of submerged membrane bioreactor (MBR) for the treatment of synthetic wastewater containing styrene as volatile organic compound (VOC): Effect of hydraulic retention time (HRT).
    N. Fallah, B. Bonakdarpour, B. Nasernejad, MR. Alavi Moghadam (2010) J. Hazard. Mater.
Baresthesia 807.64 1
  1. Long-term operation of submerged membrane bioreactor (MBR) for the treatment of synthetic wastewater containing styrene as volatile organic compound (VOC): Effect of hydraulic retention time (HRT).
    N. Fallah, B. Bonakdarpour, B. Nasernejad, MR. Alavi Moghadam (2010) J. Hazard. Mater.

Associated genes 1

Concept Name External ID Definition Weighted Score Hits References
MERTK gene EntrezGene:10461 644.0 1
  1. The kinetics of catalytic incineration of styrene over a MnO/Fe2O3 catalyst.
    TK. Tseng, H. Chu (2001) Sci. Total Environ.

Chemical Information

Formula C8H8
Mass 104.152
Synonyms STYRENE
Ethenylbenzene
Phenylethylene
100-42-5
Vinylbenzene
Styrol
Benzene, ethenyl-
Cinnamene
Phenylethene
Styrene monomer
Phenethylene
Styrolene
Vinylbenzol
Vinyl benzene
Styrole
Styren
Styropol SO
Benzene, vinyl-
Ethylene, phenyl-
Cinnamenol
Cinnamol
Vinylbenzen
Stirolo
Styreen
Diarex hf 77
Bulstren K-525-19
Annamene
Vinyl-benzene
9003-53-6
Styreen [Dutch]
Styrol [German]
Styren [Czech]
Stirolo [Italian]
NCI-C02200
Vinylbenzen [Czech]
Vinylbenzen [Dutch]
Cinnaminol
Styropol
Styron
Styrene polymer
FEMA Number 3234
Styrene (monomer)
NSC 62785
CCRIS 564
UNII-44LJ2U959V
FEMA No. 3233
Benzene, ethenyl-, homopolymer
HSDB 171
Vinylbenzene, inhibited
Phenylethylene, inhibited
EINECS 202-851-5
UN2055
Styrene monomer, inhibited
AI3-24374
CHEBI:27452
Styrol (German)
PPBRXRYQALVLMV-UHFFFAOYSA-N
44LJ2U959V
NCGC00091056-01
DSSTox_CID_1284
Styrene, analytical standard
DSSTox_RID_76057
DSSTox_GSID_21284
12770-88-6
Benzene-d5, ethenyl-d3-
Polysorb
MFCD00084450
CAS-100-42-5
Polystyrene, hydrogenated
Styropor
ethenyl-benzene
phenyl-ethylene
viny lbenzol
Benzene-1,2,3,4,5-d5, 6-(ethenyl-1,2,2-d3)-
p-vinyl benzene
Vinyl-polystyrene
Ethylenated benzene
25086-18-4
Ethylbenzene alkylate
Styron (Salt/Mix)
CARINE
Ethenylbenzene, 9CI
Styrene polymer-bound
Styropol (Salt/Mix)
Styropor (Salt/Mix)
PhCH=CH2
Styrene, >=99%
AC1L1OWJ
AC1Q2AAB
Benzene, ethenyl-, homopolymer, hydrogenated
Polystyrene med Mol. Wt.
EC 202-851-5
Polystyrene high Mol. Wt.
Diarex hf 77 (Salt/Mix)
KSC176E4F
UN 2055 (Salt/Mix)
WLN: 1U1R
BIDD:ER0247
CHEMBL285235
Styrene-divinylbenzene Copolymer
DTXSID2021284
CTK0H6242
KS-00000VQV
MolPort-001-779-766
ZINC968269
NSC62785
EINECS 273-493-5
Styrene 100 microg/mL in Methanol
Styrene, ReagentPlus(R), 99.9%
Tox21_113245
Tox21_200808
8053AF
ANW-14280
LS-304
NSC-62785
STL283958
Styrene 5000 ng/microl in Methanol
Styrene, 99%, stabilized 100ml
AKOS000119972
ZINC112958499
MCULE-4715354738
RP18837
TRA0031624
Styrene, SAJ first grade, >=99.0%
NCGC00091056-02
NCGC00091056-03
NCGC00091056-04
NCGC00091056-05
NCGC00258362-01
68441-35-0
AN-24550
BP-13451
CJ-04646
KB-60631
SC-75569
ZB015538
RT-000109
FT-0659991
FT-0689054
S0095
S0651
5487-EP2269995A1
5487-EP2270101A1
5487-EP2270113A1
5487-EP2272832A1
5487-EP2272849A1
5487-EP2272935A1
5487-EP2275418A1
5487-EP2277945A1
5487-EP2280014A2
5487-EP2284165A1
5487-EP2287168A2
5487-EP2289883A1
5487-EP2289896A1
5487-EP2292593A2
5487-EP2295415A1
5487-EP2295420A1
5487-EP2295426A1
5487-EP2295427A1
5487-EP2295438A1
5487-EP2298313A1
5487-EP2298743A1
5487-EP2298753A1
5487-EP2301924A1
5487-EP2305668A1
5487-EP2305685A1
5487-EP2305686A1
5487-EP2308832A1
5487-EP2308857A1
5487-EP2308865A1
5487-EP2309584A1
5487-EP2311796A1
5487-EP2311797A1
5487-EP2311798A1
5487-EP2311799A1
5487-EP2311804A2
5487-EP2314577A1
5487-EP2314579A1
5487-EP2380568A1
5487-EP2380867A1
C07083
C19506
Polystyrene,flame retarding and impact resistant
37291-EP2311802A1
37291-EP2311803A1
117294-EP2275408A1
117294-EP2287158A1
117294-EP2298762A2
143365-EP2287165A2
143365-EP2287166A2
143365-EP2292620A2
A800199
I01-4405
Polystyrene standard, M.W. 5,200, Mw/Mn 1.06
Polystyrene standard, M.W. 400,000, Mw/Mn 1.06
Polystyrene standard, M.W. 650,000, Mw/Mn 1.06
F1908-0130
Styrene monomer, inhibited [UN2055] [Flammable liquid]
Z966690906
Polystyrene standard, MW ~ 1,300, MW/MN = 1.06 1g
Styrene monomer, inhibited [UN2055] [Flammable liquid]
InChI=1/C8H8/c1-2-8-6-4-3-5-7-8/h2-7H,1H
Polystyrene latex microsphere, 1 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 10.0 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 15.0 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 2 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 20.0 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 25.0 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 45.0 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 6.0 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 75.0 micron, 2.5 wt% dispersion in water
Polystyrene latex microsphere, 90.0 micron, 2.5 wt% dispersion in water
Polystyrene, minimum number average molecular weight (in amu), 50,000
Styrene solution, certified reference material, 200 mug/mL in methanol
Styrene, ReagentPlus(R), contains 4-tert-butylcatechol as stabilizer, >=99%
105270-05-1
1083095-63-9
110866-50-7
11120-46-0
1160710-79-1
1161074-30-1
1187742-34-2
1191987-17-3
1198090-46-8
120037-99-2
120534-26-1
1227265-55-5
124229-31-8
124229-48-7
12627-11-1
1263545-74-9
131495-39-1
137262-45-4
144637-93-4
1453489-93-4
149212-19-1
155197-45-8
157243-21-5
157929-02-7
161776-45-0
1646200-96-5
171022-02-9
171022-09-6
172641-48-4
172867-64-0
2015955-51-6
219782-52-2
25038-60-2
260975-79-9
359762-95-1
360046-70-4
373601-20-8
39470-87-6
40494-15-3
441772-62-9
471865-10-8
487021-46-5
51609-87-1
52932-49-7
53112-49-5
53986-84-8
54578-24-4
54596-41-7
55128-06-8
55465-00-4
56451-72-0
56748-62-0
57657-06-4
58033-91-3
60120-16-3
60328-46-3
60880-98-0
61584-89-2
61584-90-5
63849-49-0
644984-36-1
726192-11-6
730985-59-8
78354-47-9
81834-12-0
851588-70-0
852837-17-3
86090-91-7
9044-64-8
9055-91-8
98444-30-5
PubChem CID 7501