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Comparison of Airway and Systemic Malondialdehyde Levels for Assessment of Oxidative Stress in Cystic Fibrosis.
B. Antus, O. Drozdovszky, I. Barta, K. Kelemen
Lung. 2015 Aug;193(4):597-604. doi: 10.1007/s00408-015-9739-1. Epub 2015 May 8.
PubMed: 25951912
Abstract
Oxidative stress plays a pivotal role in the pathogenesis of cystic fibrosis (CF). In this study, airway and systemic oxidative stress was investigated in CF using malondialdehyde (MDA), an established by-product of polyunsaturated fatty acid peroxidation. Exhaled breath condensate (EBC), sputum, and plasma were collected from 40 stable CF patients during routine clinical visits and from 25 healthy controls. MDA was measured by high-performance liquid chromatography. MDA levels in sputum (279.8 ± 14.7 vs. 92.7 ± 9.2 nmol/L, p
Associated compounds:
Compound Name
with link to compound page |
Structure | Number of references |
---|---|---|
Malondialdehyde | 91 |