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Occupational asthma due to chromium.
C. Leroyer, JD. Dewitte, A. Bassanets, M. Boutoux, C. Daniel, J. Clavier
Respiration 1998 ;65(5):403-5.
PubMed: 9782225
Abstract
We describe a 28-year-old subject employed as a roofer in a construction company since the age of 19, who developed work-related symptoms of a cough, shortness of breath, wheezing, rhinitis and headaches. A description of a usual day at work suggested that the symptoms worsened while he was sawing corrugated fiber cement. Baseline spirometry was normal, and there was a mild bronchial hyperresponsiveness to carbachol. A skin patch test to chromium was negative. A specific inhalation challenge showed a boderline fall in forced expiratory volume in 1 s (FEV1) after exposure to fiber cement dust. Exposure to nebulization of potassium dichromate (K2Cr2O7), at 0.1 mg.ml-1 for 30 min, was followed by an immediate fall by 20% FEV1. Simultaneously, a significant increase in bronchial hyperresponsiveness was demonstrated.
Associated compounds:
Compound Name
with link to compound page |
Structure | Number of references |
---|---|---|
Chromium | 24 |