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Urea production and leucine oxidation in malnourished children with and without acute infection.
MJ. Manary, KE. Yarasheski, RL. Broadhead
Metab. Clin. Exp. 2002 Nov;51(11):1418-22.
PubMed: 12404191
Abstract
We compared the kinetics of urea production and leucine oxidation in severely malnourished Malawian children. We tested the hypotheses that the rate of urea production was directly proportional to the rate of leucine oxidation and that the relationship between the two is altered by acute infection. Thirty-six marasmic children, aged 12 to 60 months, were enrolled; 26 had acute infection and 10 did not. The rates of urea and CO(2) production were estimated using primed, constant, intravenous stable isotope-labeled tracer infusions followed by intermittent sampling of breath and blood. The rate of urea production was greater in infected children when compared to uninfected children (169 +/- 85 v 105 +/- 44 micromol urea x kg(-1) x h(-1), P
Associated compounds:
Compound Name
with link to compound page |
Structure | Number of references |
---|---|---|
Urea | 1130 |