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Mastic gum has no effect on Helicobacter pylori load in vivo.
JR. Bebb, N. Bailey-Flitter, D. Ala'Aldeen, JC. Atherton
J. Antimicrob. Chemother. 2003 Sep;52(3):522-3.
PubMed: 12888582
Abstract
To determine whether mastic gum suppresses or eradicates Helicobacter pylori infection in humans. Nine patients with H. pylori infection, and without gastroduodenal ulceration, were recruited from day-case endoscopy lists and treated with mastic 1 g four times daily for 14 days. [13C]Urea breath tests (UBTs) were carried out immediately before, on day 15 and 5 weeks after treatment with mastic. Mastic had no effect on H. pylori status in any of the eight completed patients; all remained H. pylori positive by UBT with no change in delta scores [pre-treatment mean +/- s.e.m. 19.1 +/- 3.7, day 15 (post-treatment) 18.7 +/- 3.8, P = 0.8, paired t-test]. Despite reported anti-H. pylori action in vitro, this preliminary study shows that mastic has no effect on H. pylori in humans.
Associated compounds:
Compound Name
with link to compound page |
Structure | Number of references |
---|---|---|
Urea | 1130 |