15-HETE
Description
Description of 15-HETE with associated disease summary
Asthma
Higher concentrations of EBC 15-HETE were detected in asthma patients compared with healthy control (J Allergy Clin Immunol. (2011)). Although another study shows that there are no difference of EBC 15-HETE concentration between asthma patients and healthy control, the adjusted PA ratios (raw concentration divided by the concentration of palmitic acid) in asthma patients are higher than the healthy control.Asthma, Aspirin-Induced
EBC 15-HETE concentration were higher in aspirin-induced asthma (AIA) than inaspirin-tolerant patients. It can be linked to an overexpression of lipoxygenases enzymes (LO), particularly 5- and 15-LO in lungs with hypersensitivity of aspirin (J Allergy (Cairo). (2012)) .Summary of extracted biomedical information
Associated references with human 0
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Reference title
with link to reference page |
Journal | Year | Authors & PubMed Link |
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Associated curated diseases 2
Download diseasesAssociated disease mapping
Mapping of all associated diseases to 15-HETE is displayed in red.
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Disease Name
with link to disease page |
Description of MeSH term
with link to MeSH Database |
Number of references |
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| Asthma |
MeSH:
Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and
intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of
airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Link to MeSH Database: D001249
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91 |
| Aspirin Sensitive Asthma |
MeSH:
Asthma, Aspirin-Induced
Asthmatic adverse reaction (e.g., BRONCHOCONSTRICTION) to conventional NSAIDS including aspirin use.
Year introduced: 2010
Link to MeSH Database: D055963
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2 |
Associated abnormalities 0
No associated abnormalities are detected in current reference collection.
There are 0 associated references with 15-HETE. Due to lack of full text of references or no associated abnormalities are detected in our text-mining workflow, we cannot extract any abnormality terms from the associated reference collection.
Associated chemicals 0
No associated chemicals are detected in current reference collection.
There are 0 associated references with 15-HETE. Due to lack of full text of references or no associated chemicals are detected in our text-mining workflow, we cannot extract any chemical terms from the associated reference collection.
Associated functions 0
No associated functions are detected in current reference collection.
There are 0 associated references with 15-HETE. Due to lack of full text of references or no associated functions are detected in our text-mining workflow, we cannot extract any function terms from the associated reference collection.
Associated genes 0
No associated genes are detected in current reference collection.
There are 0 associated references with 15-HETE. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.
NCBI Entrez Crosslinks
Chemical Information
| Formula | C20H32O3 |
| Mass | 320.473 |
| Synonyms | 15-Hete 15-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (+/-)15-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid 73836-87-0 SCHEMBL6382058 CHEBI:64017 JSFATNQSLKRBCI-USWFWKISSA-N (+/-)15-HETE 1031AH LMFA03060087 71030-36-9 CC-00130 (5Z,8Z,11Z,13E)-15-HETE 15-hydroxy-5Z,8Z,11Z,13E-icosatetraenoic acid (5Z,8Z,11Z,13E)-15-hydroxyicosa-5,8,11,13-tetraenoic acid |
| PubChem CID | 9966861 |