Beryllium

Summary of extracted biomedical information

Beryllium is associated with abnormalities such as Berylliosis, Chronic berylliosis, immunotoxicity, Pneumonia and Sarcoidosis. The involved biomedical functions are known as Respiration, Oxidants, cytokine secretion, Exhalation and Granulomatous inflammation. Beryllium is associated with Aluminum, Metals, beryl, Metals, Light and Nitrogen.

Associated references with human 9

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Journal Year Authors & PubMed Link
Assessment of personal airborne exposures and surface contamination from x-ray vaporization of beryllium targets at the National Ignition Facility. J Occup Environ Hyg 2017 SY. Paik, PM. Epperson, KM. Kasper
J Occup Environ Hyg 2017 06;14(6):438-447. PubMed:28278063
Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries. Toxicol. Lett. 2016 A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo
Toxicol. Lett. 2016 Nov;263:26-33. PubMed:27777105
A novel alternative to environmental monitoring to detect workers at risk for beryllium exposure-related health effects. J Occup Environ Hyg 2014 E. Fireman, Y. Lerman, M. Stark, A. Pardo, Y. Schwarz, MV. Van Dyke, J. Elliot, B. Barkes, L. Newman, L. Maier
J Occup Environ Hyg 2014 ;11(12):809-18. PubMed:24856577
Development of retrospective quantitative and qualitative job-exposure matrices for exposures at a beryllium processing facility. Occup Environ Med 2011 JR. Couch, M. Petersen, C. Rice, MK. Schubauer-Berigan
Occup Environ Med 2011 May;68(5):361-5. PubMed:20974744
Beryllium aerosol characteristics in the magnesium and aluminum transformation industry in Quebec: a comparison of four different sampling methodologies. J Occup Environ Hyg 2009 A. Dufresne, C. Dion, S. Viau, Y. Cloutier, G. Perrault
J Occup Environ Hyg 2009 Nov;6(11):687-97. PubMed:19757293
Marked tachypnea in siblings with chronic beryllium disease due to copper-beryllium alloy. Chest 2001 SM. Tarlo, K. Rhee, E. Powell, E. Amer, L. Newman, G. Liss, N. Jones
Chest 2001 Feb;119(2):647-50. PubMed:11171753
Aerosols generated during beryllium machining. J. Occup. Environ. Med. 2000 JW. Martyny, MD. Hoover, MM. Mroz, K. Ellis, LA. Maier, KL. Sheff, LS. Newman
J. Occup. Environ. Med. 2000 Jan;42(1):8-18. PubMed:10652683
Machining risk of beryllium disease and sensitization with median exposures below 2 micrograms/m3. Am. J. Ind. Med. 1996 K. Kreiss, MM. Mroz, LS. Newman, J. Martyny, B. Zhen
Am. J. Ind. Med. 1996 Jul;30(1):16-25. PubMed:8837677
Serum angiotensin converting enzyme activity in chronic beryllium disease. Am. Rev. Respir. Dis. 1992 LS. Newman, R. Orton, K. Kreiss
Am. Rev. Respir. Dis. 1992 Jul;146(1):39-42. PubMed:1320822

Associated curated diseases 0

No curated diseases are identified in current reference collection.

Associated abnormalities 6

Concept Name External ID Weighted Score Hits References
Chronic berylliosis 1000.0 2
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
immunotoxicity 1000.0 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
Pneumonia 1000.0 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
Sarcoidosis ICD9-CM:135 883.5 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
Granulomatous disorder 883.5 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
Berylliosis 913.5 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.

Associated chemicals 4

Concept Name External ID Definition Weighted Score Hits References
Aluminum CHEBI:28984 934.67 3
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
beryl 1000.0 1
  1. Development of retrospective quantitative and qualitative job-exposure matrices for exposures at a beryllium processing facility.
    JR. Couch, M. Petersen, C. Rice, MK. Schubauer-Berigan (2011) Occup Environ Med
Metals, Light 961.54 1
  1. Development of retrospective quantitative and qualitative job-exposure matrices for exposures at a beryllium processing facility.
    JR. Couch, M. Petersen, C. Rice, MK. Schubauer-Berigan (2011) Occup Environ Med
Nitrogen CHEBI:17997 925.5 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.

Associated functions 4

Concept Name External ID Definition Weighted Score Hits References
Respiration 835.59 2
  1. Development of retrospective quantitative and qualitative job-exposure matrices for exposures at a beryllium processing facility.
    JR. Couch, M. Petersen, C. Rice, MK. Schubauer-Berigan (2011) Occup Environ Med
  2. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
cytokine secretion 1000.0 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
Exhalation 786.0 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.
Granulomatous inflammation 1000.0 1
  1. Effects of occupational exposure to poorly soluble forms of beryllium on biomarkers of pulmonary response in exhaled breath of workers in machining industries.
    A. Radauceanu, M. Grzebyk, JL. Edmé, N. Chérot-Kornobis, D. Rousset, M. Dziurla, V. De Broucker, G. Hédelin, A. Sobaszek, S. Hulo (2016) Toxicol. Lett.

Associated genes 0

No associated genes are detected in current reference collection.

There are 9 associated references with Beryllium. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.

Chemical Information

Formula Be
Mass 9.012
Synonyms BERYLLIUM
7440-41-7
Beryllium metal
Beryllium metallic
berilio
Beryllium dust
Beryllium powder
Beryllium-9
Beryllium, elemental
Beryllium and compounds
Beryllium, metal powder
RCRA waste number P015
CCRIS 81
UNII-OW5102UV6N
HSDB 512
Beryllium and beryllium compounds
EINECS 231-150-7
UN1566
UN1567
RCRA waste no. P015
PubChem CID 5460467