Zinc

Description

Description of Zinc with associated disease summary

Zinc is one of the metal indicators of interstitial lung diseases including sarcoidosis. Lower levels of zinc were detected in interstitial lung diseases patients. The depletion of zinc involved in the oxidant/anti-oxidant balance may be linked to the oxidative stress and chronic inflammation (J Breath Res. (2009)) In addition, higher zinc levels in lang=EN-US cystic fibrosis patients were detected compare with healthy control (J Cyst Fibros. (2003)). Description of disease(s) related to zinc:

Sarcoidosis

One study using inductive coupled plasma mass spectrometry (ICP-MS) to detect zinc and shows that the EBC zinc level in sarcoidosis patients are lower than the healthy controls (p < 0.05 versus controls) (J Breath Res. (2009)).

Cystic fibrosis

One study using inductive coupled plasma mass spectrometry (ICP-MS) to detect zinc and shows that the EBC zinc level in cystic fibrosis patients are the twice as the level in the healthy controls (p = 0.0193 versus controls) (J Cyst Fibros. (2003)).

Summary of extracted biomedical information

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Associated references with human 0

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Reference title

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Journal Year Authors & PubMed Link

Associated curated diseases 2

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Associated disease mapping

Mapping of all associated diseases to Zinc is displayed in red.

Heart Lung Airway Esophagus Kidney Intestine
Disease Name

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Description of MeSH term

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Number of references
Cystic Fibrosis MeSH: Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION. Year introduced: 1967
Link to MeSH Database: D003550
20
Sarcoidosis MeSH: Sarcoidosis
An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands. Year introduced: PSEUDOTUBERCULOSIS use SARCOIDOSIS 1963-1992
Link to MeSH Database: D012507
4

Associated abnormalities 0

No associated abnormalities are detected in current reference collection.

There are 0 associated references with Zinc. Due to lack of full text of references or no associated abnormalities are detected in our text-mining workflow, we cannot extract any abnormality terms from the associated reference collection.

Associated chemicals 0

No associated chemicals are detected in current reference collection.

There are 0 associated references with Zinc. Due to lack of full text of references or no associated chemicals are detected in our text-mining workflow, we cannot extract any chemical terms from the associated reference collection.

Associated functions 0

No associated functions are detected in current reference collection.

There are 0 associated references with Zinc. Due to lack of full text of references or no associated functions are detected in our text-mining workflow, we cannot extract any function terms from the associated reference collection.

Associated genes 0

No associated genes are detected in current reference collection.

There are 0 associated references with Zinc. Due to lack of full text of references or no associated genes are detected in our text-mining workflow, we cannot extract any gene terms from the associated reference collection.

Chemical Information

Formula Zn
Mass 65.38
Synonyms ZINC
7440-66-6
Zinc dust
Zinc powder
cinc
Merrillite
Rheinzink
Jasad
Blue powder
Granular zinc
Zinc, elemental
Emanay zinc dust
Asarco L 15
Zinc (fume or dust)
zincum
Zinc, ion (Zn1+)
Zink
Lead refinery vacuum zinc
Zinc(1+)
Zinc(1-)
PubChem CID 23994