2-ethoxy-2-methylpropane

Summary of extracted biomedical information

2-ethoxy-2-methylpropane is associated with abnormalities such as Autoimmune Syndrome Type II, Polyglandular. The involved biomedical functions are known as neuromuscular function, Cell Respiration, Mitosis, Degenerative abnormality and Pulmonary Excretion. The associated genes/proteins with 2-ethoxy-2-methylpropane are Orthologous Gene. 2-ethoxy-2-methylpropane is associated with ethyl tert-butyl ether, Toluene, 4-xylene, octane and acetonitrile.

Associated references with human 4

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Journal Year Authors & PubMed Link
A review of the volatiles from the healthy human body. J Breath Res 2014 B. de Lacy Costello, A. Amann, H. Al-Kateb, C. Flynn, W. Filipiak, T. Khalid, D. Osborne, NM. Ratcliffe
J Breath Res 2014 Mar;8(1):014001. PubMed:24421258
Exposure assessment of ETBE in gas station workers and gasoline tanker truck drivers. J Occup Health 2011 Y. Eitaki, T. Kawai, K. Omae
J Occup Health 2011 ;53(6):423-31. PubMed:21996930
TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro. Cancer Epidemiol. Biomarkers Prev. 2010 W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair
Cancer Epidemiol. Biomarkers Prev. 2010 Jan;19(1):182-95. PubMed:20056637
Toxicology and human health effects following exposure to oxygenated or reformulated gasoline. Toxicol. Lett. 2001 FE. Ahmed
Toxicol. Lett. 2001 Sep;123(2-3):89-113. PubMed:11641038

Associated curated diseases 0

No curated diseases are identified in current reference collection.

Associated abnormalities 1

Concept Name External ID Weighted Score Hits References
Autoimmune Syndrome Type II, Polyglandular 583.33 2
  1. Inverse temperature dependence of Henry's law coefficients for volatile organic compounds in supercooled water.
    K. Sieg, E. Starokozhev, MU. Schmidt, W. Püttmann (2009) Chemosphere

Associated chemicals 18

Concept Name External ID Definition Weighted Score Hits References
ethyl tert-butyl ether 666.86 16
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
  2. Inverse temperature dependence of Henry's law coefficients for volatile organic compounds in supercooled water.
    K. Sieg, E. Starokozhev, MU. Schmidt, W. Püttmann (2009) Chemosphere
  3. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
  4. Leachability of volatile fuel compounds from contaminated soils and the effect of plant exudates: A comparison of column and batch leaching tests.
    M. Balseiro-Romero, PS. Kidd, C. Monterroso (2016) J. Hazard. Mater.
Toluene CHEBI:17578 981.2 3
  1. Inverse temperature dependence of Henry's law coefficients for volatile organic compounds in supercooled water.
    K. Sieg, E. Starokozhev, MU. Schmidt, W. Püttmann (2009) Chemosphere
  2. Leachability of volatile fuel compounds from contaminated soils and the effect of plant exudates: A comparison of column and batch leaching tests.
    M. Balseiro-Romero, PS. Kidd, C. Monterroso (2016) J. Hazard. Mater.
4-xylene 967.0 2
  1. Leachability of volatile fuel compounds from contaminated soils and the effect of plant exudates: A comparison of column and batch leaching tests.
    M. Balseiro-Romero, PS. Kidd, C. Monterroso (2016) J. Hazard. Mater.
octane 895.5 2
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
  2. Inverse temperature dependence of Henry's law coefficients for volatile organic compounds in supercooled water.
    K. Sieg, E. Starokozhev, MU. Schmidt, W. Püttmann (2009) Chemosphere
acetonitrile 1000.0 2
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
pyrazole CHEBI:17241 920.0 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Deuterium 734.28 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
tertiary-amyl methyl ether 923.08 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Pyrroles 937.5 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
n-hexanal 888.89 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
isovalerylaldehyde 916.67 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
isobutyraldehyde 1000.0 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
Acetaldehyde CHEBI:15343 1000.0 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
Ketones CHEBI:17087 928.57 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
Esters CHEBI:35701 828.67 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
Aldehydes CHEBI:17478 1000.0 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
Hydrocarbons CHEBI:24632 936.0 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.
2-pentanone 1000.0 1
  1. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
    W. Filipiak, A. Sponring, A. Filipiak, C. Ager, J. Schubert, W. Miekisch, A. Amann, J. Troppmair (2010) Cancer Epidemiol. Biomarkers Prev.

Associated functions 13

Concept Name External ID Definition Weighted Score Hits References
neuromuscular function 964.73 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Cell Respiration 1000.0 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Mitosis 1000.0 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Degenerative abnormality 908.17 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Pulmonary Excretion 912.0 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Excretory function 694.0 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Hypertrophy 925.5 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Cell Proliferation 950.5 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Esthesia 1000.0 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Inspiration function 687.33 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Vapour pressure 966.67 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.
Drug Interactions 823.53 1
  1. Leachability of volatile fuel compounds from contaminated soils and the effect of plant exudates: A comparison of column and batch leaching tests.
    M. Balseiro-Romero, PS. Kidd, C. Monterroso (2016) J. Hazard. Mater.
Pressure- physical agent 666.67 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.

Associated genes 1

Concept Name External ID Definition Weighted Score Hits References
Orthologous Gene 770.25 1
  1. Toxicology and human health effects following exposure to oxygenated or reformulated gasoline.
    FE. Ahmed (2001) Toxicol. Lett.

Chemical Information

Formula C6H14O
Mass 102.177
Synonyms tert-Butyl ethyl ether
637-92-3
Ethyl tert-butyl ether
2-Ethoxy-2-methylpropane
ETBE
Propane, 2-ethoxy-2-methyl-
2-Methyl-2-ethoxypropane
Ethyl tert-butyl oxide
Ether, tert-butyl ethyl
Ethyl t-butyl ether
tert-Butylethylether
Methyl-2-ethoxypropane
2-ethoxy-2-methyl-propane
T-BUTYL ETHYL ETHER
UNII-3R9B16WR19
1,1-Dimethylethyl ethyl ether
Ethyl 1,1-dimethylethyl ether
ethyl-tert-butylether
CCRIS 6061
2-Methyl-2-ethoxypropane (etbe)
NSC 1069
EINECS 211-309-7
NUMQCACRALPSHD-UHFFFAOYSA-N
3R9B16WR19
GEO-03226
J-660063
W-109094
Ethyl-tert-butyl ether
Ethyl tertiary butyl ether
HSDB 7867
t-BuOEt
Tere-Butyl Ethyl Ether
tert-C4H9OC2H5
DSSTox_CID_5604
EC 211-309-7
AC1L1ZR3
AC1Q55PT
ACMC-1B5P9
DSSTox_RID_77850
DSSTox_GSID_25604
SCHEMBL42870
Propane,2-ethoxy-2-methyl-
KSC490I7L
tert-Butyl ethyl ether, 99%
CHEMBL1409831
DTXSID0025604
CTK3J0475
NSC1069
CHEBI:141564
MolPort-003-925-278
KS-00000X2K
NSC-1069
ZINC1587813
Tox21_200349
7559AF
ANW-34733
LS-277
AKOS015909016
ZINC100511913
FCH1117921
RTR-021931
NCGC00091556-01
NCGC00091556-02
NCGC00257903-01
AN-47022
CAS-637-92-3
CC-34757
CJ-25369
KB-61373
DB-054548
tert-Butyl ethyl ether, analytical standard
TL8004490
TR-021931
B1542
FT-0626237
74376-EP2308857A1
tert-Butyl ethyl ether, purum, >=97.0% (GC)
A834529
C-28318
I14-3407
InChI=1/C6H14O/c1-5-7-6(2,3)4/h5H2,1-4H
PubChem CID 12512